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		<title>Mi Segundo Amor</title>
		<link>http://shaizeen.wordpress.com/2011/12/28/mi-segundo-amor/</link>
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		<pubDate>Wed, 28 Dec 2011 02:35:03 +0000</pubDate>
		<dc:creator>ShaiZeen</dc:creator>
				<category><![CDATA[Algorithms]]></category>
		<category><![CDATA[Technical]]></category>

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		<description><![CDATA[                Yes.. It has happened again. Whoever said it happens only once in a lifetime was definitely lying. For a reader who has never been in the hearing distance of a Spanish speaker the title translates to &#8220;My Second love&#8221;. It is my feeble attempt to keep in touch with whatever little Spanish I have [...]<img alt="" border="0" src="http://stats.wordpress.com/b.gif?host=shaizeen.wordpress.com&amp;blog=5427472&amp;post=179&amp;subd=shaizeen&amp;ref=&amp;feed=1" width="1" height="1" />]]></description>
			<content:encoded><![CDATA[<p style="text-align:left;">                Yes.. It has happened again. Whoever said it happens only once in a lifetime was definitely lying. For a reader who has never been in the hearing distance of a Spanish speaker the title translates to &#8220;My Second love&#8221;. It is my feeble attempt to keep in touch with whatever little Spanish I have learnt so far.</p>
<p style="text-align:left;">So after heaps I wasn&#8217;t completely closed to the possibility that I will come along some idea that would leave me enamoured. Something so fundamentally beautiful that would raise the bar of what I consider an ingenious thought. And so the day came when in my Computer Architecture class at University of Michigan I was taught -</p>
<p style="text-align:center;"><em><strong>    &#8220;Register Renaming&#8221;</strong></em></p>
<p>Lets dive a little into what is this idea all about.  Modern day processors are out of order and pipelined. The first adjective essentially means that a processor, irrespective of what order the instructions are fed to it, will execute them in the order it likes to gain maximum performance and the programmer shall still see the results that he/she expects. The second adjective  simply means that the logic for each instruction is broken down into smaller pieces which can be termed as different stages in the execution.This allows us to start an  instruction before the preceding one completes as multiple instructions can be in different stages at the same time.  If the longest stage of our execution pipeline took x time units then the best possible throughput we could get is at least one instruction every x time units.</p>
<p>But there are reasons why we don&#8217;t quiet get this performance. One of these is data hazards.</p>
<p>Consider this code snippet :</p>
<p><em>        Instruction 1    : MULT R0,R0,R1        &#8211;&gt; R1    = R0 * R0</em><br />
<em>        Instruction 2    : ADD R1,R2,R3        &#8211;&gt; R3    = R1 + R2</em><br />
<em>        Instruction 3    : MULT R5,R6,R3        &#8211;&gt; R3    = R5 * R6</em><br />
<em>        Instruction 4    : ADD R7,R8,R6        &#8211;&gt; R6    = R7 + R8</em></p>
<p>Now instruction 2 cannot begin execution till instruction 1 completes because it needs the value of register R1 which instruction 1 will compute. This is RAW (Read after Write) dependency. Also, instruction 2 and 3 write to the same register R3 and even though the processor could merrily execute them out of order given they don&#8217;t effect each other we need to make sure that it is instruction 3 that writes last to register R3. This is WAW dependency (Write after Write). Finally we need to  make sure that instruction 3 reads the value of R6 before we let instruction 4 write to it. This is WAR(Write after Read) dependency. Given all this complications, our dear processor might as well execute them in order!!</p>
<p style="text-align:left;">But this is not what happens in real processors because of the amazing idea of register renaming! If we really think about it, the only true dependency is RAW.  By true what I mean is for the program to be correct, it is essential that the value computed by instruction 1 is what should actually be used by instruction 2. But  the other dependencies are just name dependencies.</p>
<p style="text-align:left;">Consider our processor had infinite registers to play around with. But to the programmers we expose only a certain set of registers. These two groups are  called : physical registers and architectural registers respectively. It is clear that ,<br />
physical registers &gt;= architectural registers</p>
<p>What register renaming does is :<br />
&#8211;Every time we encounter an instruction we give it a new physical register to write to. Essentially rename an architectural location to new physical register.<br />
&#8211;We maintain and update the mapping of architecture register -&gt; physical register accordingly.</p>
<p>Now lets assume we have 14 physical registers(P0 to P13) and 10 architectural registers (R0 to R9). Consider that the intial mapping is<br />
R0 &#8211; P0, R1 &#8211; P1 and so on.<br />
In this sunlight of register renaming (sunlight: a phenomenon which was omnipresent in my life which is now kindof extinct) our code snippet will now be:</p>
<p><em>        Instruction 1    : MULT P0,P0,P10    &#8211;&gt; mapping R1 -&gt; P1 changes to R1 -&gt; P10    </em><br />
<em>        Instruction 2    : ADD P10,P2,P11    &#8211;&gt; mapping R3 -&gt; P3 changes to R3 -&gt; P11, notice that P10 is referred here instead of P1 for R1    </em><br />
<em>        Instruction 3    : MULT P5,P6,P12    &#8211;&gt; mapping R3 -&gt; P11 changes to R3 -&gt; P12</em><br />
<em>        Instruction 4    : ADD P7,P8,P13        &#8211;&gt; mapping R6 -&gt; P6 changes to R6 -&gt; P13</em></p>
<p>So what we achieved by this is, our processor can now execute instruction 2, 3 and 4 in any order as :<br />
- WAW hazard is removed as both instruction 1 and instruction 2 have different destination registers.<br />
- WAR hazard is removed as instruction 3 will read the right value whether instruction 4 executes before it or not.</p>
<p style="text-align:left;">      That is the amazing concept of register renaming!! If you want to dig deeper here&#8217;s a well written paper : <a title="Register Renaming" href="http://www.eecs.umich.edu/eecs/courses/eecs470/papers/RegisterRenaming_Sima.pdf" target="_blank">Register Renaming Paper</a></p>
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		<title>The Impossible Dream</title>
		<link>http://shaizeen.wordpress.com/2011/03/05/the-impossible-dream/</link>
		<comments>http://shaizeen.wordpress.com/2011/03/05/the-impossible-dream/#comments</comments>
		<pubDate>Sat, 05 Mar 2011 15:44:56 +0000</pubDate>
		<dc:creator>ShaiZeen</dc:creator>
				<category><![CDATA[Literature]]></category>

		<guid isPermaLink="false">http://shaizeen.wordpress.com/?p=156</guid>
		<description><![CDATA[          Reminiscing school days with a fellow Don Bosconian at work the other day, I couldn&#8217;t help but recollect this one particular song that had a deep impact on me.  We had performed this song as part of a skit on Don Bosco. On researching about it I found that it was composed by Mitch Leigh [...]<img alt="" border="0" src="http://stats.wordpress.com/b.gif?host=shaizeen.wordpress.com&amp;blog=5427472&amp;post=156&amp;subd=shaizeen&amp;ref=&amp;feed=1" width="1" height="1" />]]></description>
			<content:encoded><![CDATA[<p style="text-align:left;">          Reminiscing school days with a fellow Don Bosconian at work the other day, I couldn&#8217;t help but recollect this one particular song that had a deep impact on me.  We had performed this song as part of a skit on Don Bosco. On researching about it I found that it was composed by Mitch Leigh and was written for the 1965 musical <em> &#8220;Man of La Mancha&#8221; </em>inspired by Miguel de Cervantes&#8217;s seventeenth century masterpiece <em>&#8220;El ingenioso hidalgo don Quijote de la Mancha&#8221;</em> ; something which is on my reading wishlist (I wish after two levels of spanish, I can read this in spanish <img src='http://s0.wp.com/wp-includes/images/smilies/icon_smile.gif' alt=':-)' class='wp-smiley' />  Que agradable pensamiento!! ).  Here are the lyrics of this beautiful song :</p>
<p style="text-align:center;">To dream the impossible dream<br />
To fight the unbeatable foe<br />
To bear with unbearable sorrow<br />
To run where the brave dare not go</p>
<p style="text-align:center;">To right the unrightable wrong<br />
To love pure and chaste from afar<br />
To try when your arms are too weary<br />
To reach the unreachable star</p>
<p style="text-align:center;">This is my quest to follow that star<br />
No matter how hopeless, no matter how far<br />
To fight for the right<br />
Without question or pause<br />
To be willing to march<br />
Into hell for a heavenly cause</p>
<p style="text-align:center;">And I know if I&#8217;ll only be true<br />
To this glorious quest<br />
That my heart will lie peaceful and calm<br />
When I&#8217;m laid to my rest</p>
<p style="text-align:center;">And the world will be better for this<br />
That one man, scorned and covered with scars<br />
Still strove with his last ounce of courage<br />
To reach the unreachable star..<br />
The fight the unbeatable foe..<br />
To dream the impossible dream..</p>
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		<title>Veintidós años alrededor del Sol</title>
		<link>http://shaizeen.wordpress.com/2010/12/05/veintidos-anos-alrededor-del-sol/</link>
		<comments>http://shaizeen.wordpress.com/2010/12/05/veintidos-anos-alrededor-del-sol/#comments</comments>
		<pubDate>Sun, 05 Dec 2010 07:40:54 +0000</pubDate>
		<dc:creator>ShaiZeen</dc:creator>
				<category><![CDATA[Personal]]></category>
		<category><![CDATA[Travel]]></category>

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		<description><![CDATA[Its been long that I have come here. I had somehow lost any appetite to blog.  But well here I am again . Needless to say much has changed in the interim. But this post is primarily about my recent trip with my friends. Transition from college life to a work life had taken both [...]<img alt="" border="0" src="http://stats.wordpress.com/b.gif?host=shaizeen.wordpress.com&amp;blog=5427472&amp;post=136&amp;subd=shaizeen&amp;ref=&amp;feed=1" width="1" height="1" />]]></description>
			<content:encoded><![CDATA[<p>    Its been long that I have come here. I had somehow lost any appetite to blog.  But well here I am again <img src='http://s0.wp.com/wp-includes/images/smilies/icon_smile.gif' alt=':-)' class='wp-smiley' /> . Needless to say much has changed in the interim. But this post is primarily about my recent trip with my friends.</p>
<p> Transition from college life to a work life had taken both me and my friends to different cities with technology as the only means to keep in touch. We always tried to plan a re-union but trust me getting 4 different outlook calendars to show <em>&#8216;free&#8217;</em> in the same time slot is a herculean task and takes a lot of concerted effort  (add planning vacation with your boss to that and you know I am talking of exponential complexity here <img src='http://s0.wp.com/wp-includes/images/smilies/icon_smile.gif' alt=':-)' class='wp-smiley' />  ). But finally, more than a year after graduating from college we all hatched a plan to get out of our rat races and headed to my hometown ; the beautiful and scenic Konkan region. </p>
<p>It was my birthday and our plan was to have a small celebration with my family and spend the weekend in Goa and Malvan. So after Day 1 of birthday celebrations and munching on my Mother&#8217;s delicacies we started pretty early for Goa the next day. Goa is about 90Km from my place and well connected by the NH17 national highway. Along the way we were mesmerized by  beautiful Moti Talav (Lake) in Sawantwadi and overlooking it was the famous Rajwada. We decided to visit the famous Calangute beach in Goa first. It was quiet crowded by the time we reached there and water sports were in full swing. Looking at the fun and frolic around we dropped our initial plan to indulge in water sports at the Dona Paula beach and grabbed the first water scooter in sight <img src='http://s0.wp.com/wp-includes/images/smilies/icon_smile.gif' alt=':-)' class='wp-smiley' />  .</p>
<p>Boy.. I don&#8217;t remember the last time I must have been so thrilled!!! Being never fond of sports, I was a bit apprehensive initially but my friends were adamant that they were going to make me start a new year of my life with as much as craziness as possible; with the <em>&#8216;scary&#8217;</em> Banana ride or <em>&#8216;you are the king of world&#8217;</em> Para sailing ride or <em>&#8216;get spanked&#8217; </em>Bumping ride !! After completely exhausting ourselves we headed to Panjim for lunch. Walking on the June 18 Road and interacting with a host of locals we were advised to go to the &#8216;Ritz Hotel&#8217; for authentic Goan food. My <em>fishetarian</em> friend enjoyed the <em>&#8216;fish plate&#8217;</em> there,  (5 delicious varieties of fish in one plate.. all she could say was <em>&#8216;I am loving it&#8217;</em>) while I was left mulling over the fact that my sweet lime juice cost as much as the some varieties of booze there!! We headed to Old Goa after that; for a trip to Goa is never complete for me till I visit the famous Basilica Of Bom Jesus. After spending a calm evening on the Miramar beach we headed for home to take some rest before another excited day began.</p>
<p>Day 3 of our trip was dedicated to exploring beaches in Malvan, again an hour&#8217;s ride from my place.  We reached there early in morning and after hiring a boat we headed to the &#8216;Dolphin point&#8217;  about 9 Km in the sea through the back waters.  It was there,  for the first time in our lives that we saw the amazing symmetry with which dolphins swim !! We were left spellbound by the beauty of their movement which was over-powering the vastness of the ocean. It was only when the cruel and unstoppable <em>&#8216;Time&#8217; </em>shone on our heads in the form of Sun that we   headed back to the shore. After a short visit to the famous and serene Tarkarli beach we headed to the Malvan Jetty to do something we all were mightily excited about &#8211; Snorkeling!!  Snorkeling is a recently started activity near the Sindhudurg fort. Our guides were two patient individuals who calmly explained us how to use our gear. Well, after that it was but Discovery live for you!!! We saw different varieties of corals and many beautiful fishes.  We ended our Day-3 trip by a visit to the famous Sindhudurg fort.</p>
<p>All in all it was a near perfect start of a new year for me; all cause of my lovely and energetic buddies. Love you all big time girls <img src='http://s0.wp.com/wp-includes/images/smilies/icon_smile.gif' alt=':-)' class='wp-smiley' /> </p>
<p>&nbsp;</p>
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		<title>Moving on&#8230;</title>
		<link>http://shaizeen.wordpress.com/2009/07/29/moving-on/</link>
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		<pubDate>Wed, 29 Jul 2009 06:50:06 +0000</pubDate>
		<dc:creator>ShaiZeen</dc:creator>
				<category><![CDATA[Events]]></category>
		<category><![CDATA[Personal]]></category>
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		<category><![CDATA[Imagine Cup]]></category>
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		<description><![CDATA[First of all many thanks to a friend who took the pains to mail me that she happened to read my blog and that I should keep writing. They say &#8216;a friend is someone who knows the song in your heart and can sing it back to you when you have forgotten the words&#8217;. Thanks [...]<img alt="" border="0" src="http://stats.wordpress.com/b.gif?host=shaizeen.wordpress.com&amp;blog=5427472&amp;post=94&amp;subd=shaizeen&amp;ref=&amp;feed=1" width="1" height="1" />]]></description>
			<content:encoded><![CDATA[<p style="text-align:left;">
<p style="text-align:left;">First of all many thanks to a friend who took the pains to mail me that she happened to read my blog and that I should keep writing. They say &#8216;a friend is someone who knows the song in your heart and can sing it back to you when you have forgotten the words&#8217;. Thanks to her that I finally felt like posting this one. So many things have happened in the past 2 months that I guess it took some time for me to come to terms with myself. Here&#8217;s a quick list:</p>
<ol style="text-align:left;">
<li> I finished my engineering studies with static colors <img src='http://s0.wp.com/wp-includes/images/smilies/icon_smile.gif' alt=':)' class='wp-smiley' /> . So now I can claim that I am an Engineer. Shaizeen Aga, BTech IT (COEP) happens to be my new designation <img src='http://s0.wp.com/wp-includes/images/smilies/icon_smile.gif' alt=':)' class='wp-smiley' /> .</li>
<li>We, which means (Akki, Swati and me) won Imagine Cup Parallel Computing Award. I really want to thank some people without whom this achievement would not have been possible.<strong>-Niks:</strong> For suggesting to me that I participate ( I had better mention Shira&#8217;s name here for inviting us to her birthday party and coming late herself <img src='http://s0.wp.com/wp-includes/images/smilies/icon_smile.gif' alt=':)' class='wp-smiley' />  which gave Niks and me, the time to start chatting). He not only suggested that I participate but also wholeheartedly believed that I would win <img src='http://s0.wp.com/wp-includes/images/smilies/icon_smile.gif' alt=':)' class='wp-smiley' /> . Niks, do let me know how you developed this foresight:).
<p><strong>-Sudhir:</strong> For answering all my silly doubts with his immense patience and helping out.</p>
<p><strong>-Jinson and Kumbhar Sir:</strong> For helping us arrange a quad core machine for getting our test results.</p>
<p>-And last but not the least <strong>Swati</strong>, for having a dual core machine, almost killing it for getting the results we got and for converting herself into a anthropomorphic debugger for almost over a month to make our code run with atmost precision and<strong> Akki</strong> for being at a &#8216;missed call&#8217; distance from me for last four years and  bearing up with PRETCT who almost used to throw up (or faint) when fed with our code and large datasets.</li>
<li>I had my first press conference for winning the Imagine Cup which was arranged by our college. Here&#8217;s a short list of various  newspapers covering this:<br />
<a href="http://www.punemirror.in/index.aspx?page=article&amp;sectid=62&amp;contentid=200906152009061503270386ba5097f0">Pune Mirror</a><a href="http://www.indianexpress.com/news/coep-students-bag-microsoft-imagine-cup/481490/">Indian Express</a></p>
<p><a href="http://timesofindia.indiatimes.com/NEWS/City/Pune/COEP-bags-first-spot-in-intl-student-tech-event/articleshow/4736316.cms">Times of India</a></li>
<li>I moved out of Pune and I am back at home now. I definitely miss the city a lot&#8230; esp Smokin Joes, Corn Club, Horn Ok Please, Krishna Juice Center, ABC, J-Block and most of all C-O-E-P&#8230; The last four years have been some of the best years of my life and they wouldn&#8217;t have been so had it not been for all my beloved friends who made it so for me. I miss you all a lot&#8230; <img src='http://s0.wp.com/wp-includes/images/smilies/icon_sad.gif' alt=':(' class='wp-smiley' /> </li>
</ol>
<p>Life at home is good.. Rain gods are pouring their hearts out and it rains cats and dogs out here&#8230; I have never been a devout  Sun Fan  nor a Rain Fan , but I surely am  missing  Sun a lot <img src='http://s0.wp.com/wp-includes/images/smilies/icon_sad.gif' alt=':(' class='wp-smiley' />  . If any you guys happen to see him please let him know I am heart-broken and that he should try striking some sort of pact with Rain and show up atleast for a few hours everyday. I am waiting for the hegemony of Rain god to end and for my mornings to be welcomed by the dulcet sounds of birds instead of the constant clamor of incessant rains.</p>
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			<media:title type="html">shaizeen</media:title>
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		<title>Shaiz votes!!</title>
		<link>http://shaizeen.wordpress.com/2009/04/23/shaiz-votes/</link>
		<comments>http://shaizeen.wordpress.com/2009/04/23/shaiz-votes/#comments</comments>
		<pubDate>Thu, 23 Apr 2009 17:13:53 +0000</pubDate>
		<dc:creator>ShaiZeen</dc:creator>
				<category><![CDATA[Events]]></category>
		<category><![CDATA[Personal]]></category>
		<category><![CDATA[election]]></category>
		<category><![CDATA[Vote]]></category>

		<guid isPermaLink="false">http://shaizeen.wordpress.com/?p=77</guid>
		<description><![CDATA[Where have I been in the last one month? Yes. Same stuff, submission (just 1 this time though) and viva. But I think the buggy-ness quotient of this one submission was really high as compared to the other submissions that we have had. And yes of course my project report submission. Jeez… Documentation is a [...]<img alt="" border="0" src="http://stats.wordpress.com/b.gif?host=shaizeen.wordpress.com&amp;blog=5427472&amp;post=77&amp;subd=shaizeen&amp;ref=&amp;feed=1" width="1" height="1" />]]></description>
			<content:encoded><![CDATA[<p style="text-align:left;"><!--[if gte mso 9]&gt;  Normal 0     false false false  EN-US X-NONE X-NONE              MicrosoftInternetExplorer4              &lt;![endif]--><!--[if gte mso 9]&gt;                                                                                                                                            &lt;![endif]--><!--  /* Font Definitions */  @font-face 	{font-family:Wingdings; 	panose-1:5 0 0 0 0 0 0 0 0 0; 	mso-font-charset:2; 	mso-generic-font-family:auto; 	mso-font-pitch:variable; 	mso-font-signature:0 268435456 0 0 -2147483648 0;} @font-face 	{font-family:"Cambria Math"; 	panose-1:2 4 5 3 5 4 6 3 2 4; 	mso-font-charset:0; 	mso-generic-font-family:roman; 	mso-font-pitch:variable; 	mso-font-signature:-1610611985 1107304683 0 0 159 0;} @font-face 	{font-family:Calibri; 	panose-1:2 15 5 2 2 2 4 3 2 4; 	mso-font-charset:0; 	mso-generic-font-family:swiss; 	mso-font-pitch:variable; 	mso-font-signature:-1610611985 1073750139 0 0 159 0;}  /* Style Definitions */  p.MsoNormal, li.MsoNormal, div.MsoNormal 	{mso-style-unhide:no; 	mso-style-qformat:yes; 	mso-style-parent:""; 	margin-top:0in; 	margin-right:0in; 	margin-bottom:10.0pt; 	margin-left:0in; 	line-height:115%; 	mso-pagination:widow-orphan; 	font-size:11.0pt; 	font-family:"Calibri","sans-serif"; 	mso-ascii-font-family:Calibri; 	mso-ascii-theme-font:minor-latin; 	mso-fareast-font-family:Calibri; 	mso-fareast-theme-font:minor-latin; 	mso-hansi-font-family:Calibri; 	mso-hansi-theme-font:minor-latin; 	mso-bidi-font-family:"Times New Roman"; 	mso-bidi-theme-font:minor-bidi;} .MsoChpDefault 	{mso-style-type:export-only; 	mso-default-props:yes; 	mso-ascii-font-family:Calibri; 	mso-ascii-theme-font:minor-latin; 	mso-fareast-font-family:Calibri; 	mso-fareast-theme-font:minor-latin; 	mso-hansi-font-family:Calibri; 	mso-hansi-theme-font:minor-latin; 	mso-bidi-font-family:"Times New Roman"; 	mso-bidi-theme-font:minor-bidi;} .MsoPapDefault 	{mso-style-type:export-only; 	margin-bottom:10.0pt; 	line-height:115%;} @page Section1 	{size:8.5in 11.0in; 	margin:1.0in 1.0in 1.0in 1.0in; 	mso-header-margin:.5in; 	mso-footer-margin:.5in; 	mso-paper-source:0;} div.Section1 	{page:Section1;} --><!--[if gte mso 10]&gt; &lt;!   /* Style Definitions */  table.MsoNormalTable 	{mso-style-name:"Table Normal"; 	mso-tstyle-rowband-size:0; 	mso-tstyle-colband-size:0; 	mso-style-noshow:yes; 	mso-style-priority:99; 	mso-style-qformat:yes; 	mso-style-parent:""; 	mso-padding-alt:0in 5.4pt 0in 5.4pt; 	mso-para-margin-top:0in; 	mso-para-margin-right:0in; 	mso-para-margin-bottom:10.0pt; 	mso-para-margin-left:0in; 	line-height:115%; 	mso-pagination:widow-orphan; 	font-size:11.0pt; 	font-family:"Calibri","sans-serif"; 	mso-ascii-font-family:Calibri; 	mso-ascii-theme-font:minor-latin; 	mso-fareast-font-family:"Times New Roman"; 	mso-fareast-theme-font:minor-fareast; 	mso-hansi-font-family:Calibri; 	mso-hansi-theme-font:minor-latin;} --> <!--[endif]--><span style="font-size:11pt;line-height:115%;font-family:&quot;"> </span></p>
<p style="text-align:left;"><span style="font-size:11pt;line-height:115%;font-family:&quot;"> Where have I been in the last one month? Yes. Same stuff, submission (just 1 this time though</span><span style="font-size:11pt;line-height:115%;font-family:&quot;">) and viva. But I think the buggy-ness quotient of this one submission was really high as compared to the other submissions that we have had. And yes of course my project report submission. Jeez… Documentation is a herculean task and by no means should be done at eleventh hour. But I never had documented any stuff and so creating the report really took the breath out of me. &#8216;Digging a well only when thirsty&#8217; is definitely not a right way to quench your thirst. <img src='http://s0.wp.com/wp-includes/images/smilies/icon_smile.gif' alt=':)' class='wp-smiley' /> </span></p>
<p style="text-align:left;"><!--[if gte mso 9]&gt;  Normal 0     false false false  EN-US X-NONE X-NONE              MicrosoftInternetExplorer4              &lt;![endif]--><!--[if gte mso 9]&gt;                                                                                                                                            &lt;![endif]--><!--  /* Font Definitions */  @font-face 	{font-family:Wingdings; 	panose-1:5 0 0 0 0 0 0 0 0 0; 	mso-font-charset:2; 	mso-generic-font-family:auto; 	mso-font-pitch:variable; 	mso-font-signature:0 268435456 0 0 -2147483648 0;} @font-face 	{font-family:"Cambria Math"; 	panose-1:2 4 5 3 5 4 6 3 2 4; 	mso-font-charset:0; 	mso-generic-font-family:roman; 	mso-font-pitch:variable; 	mso-font-signature:-1610611985 1107304683 0 0 159 0;} @font-face 	{font-family:Calibri; 	panose-1:2 15 5 2 2 2 4 3 2 4; 	mso-font-charset:0; 	mso-generic-font-family:swiss; 	mso-font-pitch:variable; 	mso-font-signature:-1610611985 1073750139 0 0 159 0;}  /* Style Definitions */  p.MsoNormal, li.MsoNormal, div.MsoNormal 	{mso-style-unhide:no; 	mso-style-qformat:yes; 	mso-style-parent:""; 	margin-top:0in; 	margin-right:0in; 	margin-bottom:10.0pt; 	margin-left:0in; 	line-height:115%; 	mso-pagination:widow-orphan; 	font-size:11.0pt; 	font-family:"Calibri","sans-serif"; 	mso-ascii-font-family:Calibri; 	mso-ascii-theme-font:minor-latin; 	mso-fareast-font-family:Calibri; 	mso-fareast-theme-font:minor-latin; 	mso-hansi-font-family:Calibri; 	mso-hansi-theme-font:minor-latin; 	mso-bidi-font-family:"Times New Roman"; 	mso-bidi-theme-font:minor-bidi;} .MsoChpDefault 	{mso-style-type:export-only; 	mso-default-props:yes; 	mso-ascii-font-family:Calibri; 	mso-ascii-theme-font:minor-latin; 	mso-fareast-font-family:Calibri; 	mso-fareast-theme-font:minor-latin; 	mso-hansi-font-family:Calibri; 	mso-hansi-theme-font:minor-latin; 	mso-bidi-font-family:"Times New Roman"; 	mso-bidi-theme-font:minor-bidi;} .MsoPapDefault 	{mso-style-type:export-only; 	margin-bottom:10.0pt; 	line-height:115%;} @page Section1 	{size:8.5in 11.0in; 	margin:1.0in 1.0in 1.0in 1.0in; 	mso-header-margin:.5in; 	mso-footer-margin:.5in; 	mso-paper-source:0;} div.Section1 	{page:Section1;} --><!--[if gte mso 10]&gt; &lt;!   /* Style Definitions */  table.MsoNormalTable 	{mso-style-name:"Table Normal"; 	mso-tstyle-rowband-size:0; 	mso-tstyle-colband-size:0; 	mso-style-noshow:yes; 	mso-style-priority:99; 	mso-style-qformat:yes; 	mso-style-parent:""; 	mso-padding-alt:0in 5.4pt 0in 5.4pt; 	mso-para-margin-top:0in; 	mso-para-margin-right:0in; 	mso-para-margin-bottom:10.0pt; 	mso-para-margin-left:0in; 	line-height:115%; 	mso-pagination:widow-orphan; 	font-size:11.0pt; 	font-family:"Calibri","sans-serif"; 	mso-ascii-font-family:Calibri; 	mso-ascii-theme-font:minor-latin; 	mso-fareast-font-family:"Times New Roman"; 	mso-fareast-theme-font:minor-fareast; 	mso-hansi-font-family:Calibri; 	mso-hansi-theme-font:minor-latin;} --> <!--[endif]--></p>
<p class="MsoNormal" style="text-indent:.5in;text-align:left;">As usual everything is done and I think was done well. But this week has been completely packed with some really important stuff for me. First on Tuesday we had Graduation day at the Akanksha center I volunteer for. This is a day when kids graduate from one level to next and demonstrate what they have learned in the present term. The kids were so enthusiastic about what they were presenting. It was fun attending it but at the same time it reminded me that I won’t be seeing them anymore as the center will be closed for summer holidays. I am sure gonna miss them <span style="font-family:Wingdings;"><span> <img src='http://s0.wp.com/wp-includes/images/smilies/icon_sad.gif' alt=':(' class='wp-smiley' /> </span></span>.</p>
<p class="MsoNormal" style="text-indent:.5in;text-align:left;">Second (n really important) was today I cast my first vote. I am really so happy and proud about this<span style="font-family:Wingdings;"><span> <img src='http://s0.wp.com/wp-includes/images/smilies/icon_smile.gif' alt=':)' class='wp-smiley' /> </span></span>. Thanks to my roomies (Trups, Shitu, Appulocks) for letting me know that we could register for voting in Pune even though we aren’t permanently residing here. Also special thanks to “Jaago Re! One Billion Votes”, the non-partisan national campaign launched by Janaagraha Centre for Citizenship and Democracy and Tata Tea for making it so simple to register for voting. So,</p>
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<p class="MsoNormal" style="margin-bottom:.0001pt;text-indent:.5in;line-height:normal;text-align:center;">“Here we stand with a dot,</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;text-indent:.5in;line-height:normal;text-align:center;">Proud that we added our tot <span style="font-family:Wingdings;"><span> <img src='http://s0.wp.com/wp-includes/images/smilies/icon_smile.gif' alt=':)' class='wp-smiley' /> </span></span>”</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;text-indent:.5in;line-height:normal;text-align:center;">
<div id="attachment_78" class="wp-caption aligncenter" style="width: 160px"><img class="size-thumbnail wp-image-78" title="Election day" src="http://shaizeen.files.wordpress.com/2009/04/image236.jpg?w=150&#038;h=150" alt="Us after voting" width="150" height="150" /><p class="wp-caption-text">Us after voting</p></div>
<p class="MsoNormal" style="text-indent:.5in;text-align:left;"><!--[if gte mso 9]&gt;  Normal 0     false false false  EN-US X-NONE X-NONE              MicrosoftInternetExplorer4              &lt;![endif]--><!--[if gte mso 9]&gt;                                                                                                                                            &lt;![endif]--><!--  /* Font Definitions */  @font-face 	{font-family:"Cambria Math"; 	panose-1:2 4 5 3 5 4 6 3 2 4; 	mso-font-charset:0; 	mso-generic-font-family:roman; 	mso-font-pitch:variable; 	mso-font-signature:-1610611985 1107304683 0 0 159 0;} @font-face 	{font-family:Calibri; 	panose-1:2 15 5 2 2 2 4 3 2 4; 	mso-font-charset:0; 	mso-generic-font-family:swiss; 	mso-font-pitch:variable; 	mso-font-signature:-1610611985 1073750139 0 0 159 0;}  /* Style Definitions */  p.MsoNormal, li.MsoNormal, div.MsoNormal 	{mso-style-unhide:no; 	mso-style-qformat:yes; 	mso-style-parent:""; 	margin-top:0in; 	margin-right:0in; 	margin-bottom:10.0pt; 	margin-left:0in; 	line-height:115%; 	mso-pagination:widow-orphan; 	font-size:11.0pt; 	font-family:"Calibri","sans-serif"; 	mso-ascii-font-family:Calibri; 	mso-ascii-theme-font:minor-latin; 	mso-fareast-font-family:Calibri; 	mso-fareast-theme-font:minor-latin; 	mso-hansi-font-family:Calibri; 	mso-hansi-theme-font:minor-latin; 	mso-bidi-font-family:"Times New Roman"; 	mso-bidi-theme-font:minor-bidi;} .MsoChpDefault 	{mso-style-type:export-only; 	mso-default-props:yes; 	mso-ascii-font-family:Calibri; 	mso-ascii-theme-font:minor-latin; 	mso-fareast-font-family:Calibri; 	mso-fareast-theme-font:minor-latin; 	mso-hansi-font-family:Calibri; 	mso-hansi-theme-font:minor-latin; 	mso-bidi-font-family:"Times New Roman"; 	mso-bidi-theme-font:minor-bidi;} .MsoPapDefault 	{mso-style-type:export-only; 	margin-bottom:10.0pt; 	line-height:115%;} @page Section1 	{size:8.5in 11.0in; 	margin:1.0in 1.0in 1.0in 1.0in; 	mso-header-margin:.5in; 	mso-footer-margin:.5in; 	mso-paper-source:0;} div.Section1 	{page:Section1;} --><!--[if gte mso 10]&gt; &lt;!   /* Style Definitions */  table.MsoNormalTable 	{mso-style-name:"Table Normal"; 	mso-tstyle-rowband-size:0; 	mso-tstyle-colband-size:0; 	mso-style-noshow:yes; 	mso-style-priority:99; 	mso-style-qformat:yes; 	mso-style-parent:""; 	mso-padding-alt:0in 5.4pt 0in 5.4pt; 	mso-para-margin-top:0in; 	mso-para-margin-right:0in; 	mso-para-margin-bottom:10.0pt; 	mso-para-margin-left:0in; 	line-height:115%; 	mso-pagination:widow-orphan; 	font-size:11.0pt; 	font-family:"Calibri","sans-serif"; 	mso-ascii-font-family:Calibri; 	mso-ascii-theme-font:minor-latin; 	mso-fareast-font-family:"Times New Roman"; 	mso-fareast-theme-font:minor-fareast; 	mso-hansi-font-family:Calibri; 	mso-hansi-theme-font:minor-latin;} --> <!--[endif]--><span style="font-size:11pt;line-height:115%;font-family:&quot;">And finally now I think I will retire to studying something as the last important (??) thing this week is my end semester exam on Saturday. It&#8217;s high time and I should better start digging now <img src='http://s0.wp.com/wp-includes/images/smilies/icon_smile.gif' alt=':)' class='wp-smiley' /><br />
</span></p>
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		<slash:comments>6</slash:comments>
	
		<media:content url="" medium="image">
			<media:title type="html">shaizeen</media:title>
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		<media:content url="http://shaizeen.files.wordpress.com/2009/04/image236.jpg?w=76" medium="image">
			<media:title type="html">Election day</media:title>
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	</item>
		<item>
		<title>Shaiz Aligned!!</title>
		<link>http://shaizeen.wordpress.com/2009/03/12/shaiz-aligned/</link>
		<comments>http://shaizeen.wordpress.com/2009/03/12/shaiz-aligned/#comments</comments>
		<pubDate>Thu, 12 Mar 2009 09:04:50 +0000</pubDate>
		<dc:creator>ShaiZeen</dc:creator>
				<category><![CDATA[Algorithms]]></category>
		<category><![CDATA[Technical]]></category>
		<category><![CDATA[Bioinformatics]]></category>
		<category><![CDATA[pairwise sequence alignment]]></category>
		<category><![CDATA[Smith- Waterman Algorithm]]></category>

		<guid isPermaLink="false">http://shaizeen.wordpress.com/?p=52</guid>
		<description><![CDATA[In our final year of engineering we are given the liberty to choose from a set of subjects as to be our &#8220;elective&#8221;. Now elective is a choice&#8230; It&#8217;s a choice you make based on what your interests are and you are &#8220;expected&#8221; to be interested in something which the college offers you. It is [...]<img alt="" border="0" src="http://stats.wordpress.com/b.gif?host=shaizeen.wordpress.com&amp;blog=5427472&amp;post=52&amp;subd=shaizeen&amp;ref=&amp;feed=1" width="1" height="1" />]]></description>
			<content:encoded><![CDATA[<p><!--[if gte mso 9]&gt;  Normal 0     false false false  EN-US X-NONE X-NONE                           &lt;![endif]--><!--[if gte mso 9]&gt;                                                                                                                                            &lt;![endif]--> <!--[if gte mso 10]&gt; &lt;!   /* Style Definitions */  table.MsoNormalTable 	{mso-style-name:"Table Normal"; 	mso-tstyle-rowband-size:0; 	mso-tstyle-colband-size:0; 	mso-style-noshow:yes; 	mso-style-priority:99; 	mso-style-qformat:yes; 	mso-style-parent:""; 	mso-padding-alt:0in 5.4pt 0in 5.4pt; 	mso-para-margin-top:0in; 	mso-para-margin-right:0in; 	mso-para-margin-bottom:10.0pt; 	mso-para-margin-left:0in; 	line-height:115%; 	mso-pagination:widow-orphan; 	font-size:11.0pt; 	font-family:"Calibri","sans-serif"; 	mso-ascii-font-family:Calibri; 	mso-ascii-theme-font:minor-latin; 	mso-hansi-font-family:Calibri; 	mso-hansi-theme-font:minor-latin;} --> <!--[endif]--></p>
<p class="MsoNormal" style="text-indent:.5in;">In our final year of engineering we are given the liberty to choose from a set of subjects as to be our &#8220;elective&#8221;. Now elective is a choice&#8230; It&#8217;s a choice you make based on what your interests are and you are &#8220;expected&#8221; to be interested in something which the college offers you. It is an altogether different issue that college always offers something boring and students are always never sure of what they are interested in and hence usually prefer to take a course wherein teachers don’t turn up.</p>
<p class="MsoNormal" style="text-indent:.5in;">Entering into my final semester of engineering I was sure of what my interests are but I was also sure college authorities wouldn’t have anything to offer that would interest me. But scrolling through the list put up at department notice board, I found a new offering. “Computational Biology”. The syllabus seemed interesting (it had algorithms). Most importantly it was going to be taught by people from the industry. I really appreciate people from industry who volunteer for teaching assignments. Taking time out of their busy schedule to interact with students is indeed commendable. Besides I have always being in favor of continuous interaction between academia and industry. Producers and consumers should always be in sync with each other. So I signed in for the course.</p>
<p><span style="font-size:11pt;font-family:&quot;">And so in my final semester of engineering I was admitted to a school</span><span style="font-size:11pt;font-family:&quot;">.I experienced things which I last saw/felt in high school.</span><span style="font-size:11pt;font-family:&quot;"> </span><!--[if gte mso 9]&gt;  Normal 0     false false false  EN-US X-NONE X-NONE                           &lt;![endif]--><!--[if gte mso 9]&gt;                                                                                                                                            &lt;![endif]--></p>
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<p class="MsoListParagraph" style="margin-left:1in;text-indent:-.25in;"><!--[if !supportLists]-->All the course instructors always come on time</p>
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	mso-hansi-font-family:Calibri; 	mso-hansi-theme-font:minor-latin; 	mso-bidi-font-family:"Times New Roman"; 	mso-bidi-theme-font:minor-bidi;} .MsoChpDefault 	{mso-style-type:export-only; 	mso-default-props:yes; 	mso-ascii-font-family:Calibri; 	mso-ascii-theme-font:minor-latin; 	mso-fareast-font-family:Calibri; 	mso-fareast-theme-font:minor-latin; 	mso-hansi-font-family:Calibri; 	mso-hansi-theme-font:minor-latin; 	mso-bidi-font-family:"Times New Roman"; 	mso-bidi-theme-font:minor-bidi;} .MsoPapDefault 	{mso-style-type:export-only; 	margin-bottom:10.0pt; 	line-height:115%;} @page Section1 	{size:8.5in 11.0in; 	margin:1.0in 1.0in 1.0in 1.0in; 	mso-header-margin:.5in; 	mso-footer-margin:.5in; 	mso-paper-source:0;} div.Section1 	{page:Section1;}  /* List Definitions */  @list l0 	{mso-list-id:166099303; 	mso-list-type:hybrid; 	mso-list-template-ids:-2040099492 67698699 67698691 67698693 67698689 67698691 67698693 67698689 67698691 67698693;} @list l0:level1 	{mso-level-number-format:bullet; 	mso-level-text:; 	mso-level-tab-stop:none; 	mso-level-number-position:left; 	margin-left:1.0in; 	text-indent:-.25in; 	font-family:Wingdings;} ol 	{margin-bottom:0in;} ul 	{margin-bottom:0in;} --><!--[if gte mso 10]&gt; &lt;!   /* Style Definitions */  table.MsoNormalTable 	{mso-style-name:"Table Normal"; 	mso-tstyle-rowband-size:0; 	mso-tstyle-colband-size:0; 	mso-style-noshow:yes; 	mso-style-priority:99; 	mso-style-qformat:yes; 	mso-style-parent:""; 	mso-padding-alt:0in 5.4pt 0in 5.4pt; 	mso-para-margin-top:0in; 	mso-para-margin-right:0in; 	mso-para-margin-bottom:10.0pt; 	mso-para-margin-left:0in; 	line-height:115%; 	mso-pagination:widow-orphan; 	font-size:11.0pt; 	font-family:"Calibri","sans-serif"; 	mso-ascii-font-family:Calibri; 	mso-ascii-theme-font:minor-latin; 	mso-hansi-font-family:Calibri; 	mso-hansi-theme-font:minor-latin;} --> <!--[endif]-->
<p class="MsoListParagraph" style="margin-left:1in;text-indent:-.25in;"><!--[if !supportLists]--><span style="font-family:Wingdings;"><span><span style="font-family:&quot;font-style:normal;font-variant:normal;font-weight:normal;font-size:7pt;line-height:normal;"> </span></span></span><!--[endif]-->Basically they never miss any of their allotted slots<span style="font-family:Wingdings;"><span> </span></span>i.e. lectures take place as per schedule.</p>
</li>
<li><!--[if gte mso 9]&gt;  Normal 0     false false false  EN-US X-NONE X-NONE                           &lt;![endif]--><!--[if gte mso 9]&gt;                                                                                                                                            &lt;![endif]--><!--  /* Font Definitions */  @font-face 	{font-family:Wingdings; 	panose-1:5 0 0 0 0 0 0 0 0 0; 	mso-font-charset:2; 	mso-generic-font-family:auto; 	mso-font-pitch:variable; 	mso-font-signature:0 268435456 0 0 -2147483648 0;} @font-face 	{font-family:"Cambria Math"; 	panose-1:2 4 5 3 5 4 6 3 2 4; 	mso-font-charset:0; 	mso-generic-font-family:roman; 	mso-font-pitch:variable; 	mso-font-signature:-1610611985 1107304683 0 0 159 0;} @font-face 	{font-family:Calibri; 	panose-1:2 15 5 2 2 2 4 3 2 4; 	mso-font-charset:0; 	mso-generic-font-family:swiss; 	mso-font-pitch:variable; 	mso-font-signature:-1610611985 1073750139 0 0 159 0;}  /* Style Definitions */  p.MsoNormal, li.MsoNormal, div.MsoNormal 	{mso-style-unhide:no; 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	mso-hansi-font-family:Calibri; 	mso-hansi-theme-font:minor-latin; 	mso-bidi-font-family:"Times New Roman"; 	mso-bidi-theme-font:minor-bidi;} .MsoChpDefault 	{mso-style-type:export-only; 	mso-default-props:yes; 	mso-ascii-font-family:Calibri; 	mso-ascii-theme-font:minor-latin; 	mso-fareast-font-family:Calibri; 	mso-fareast-theme-font:minor-latin; 	mso-hansi-font-family:Calibri; 	mso-hansi-theme-font:minor-latin; 	mso-bidi-font-family:"Times New Roman"; 	mso-bidi-theme-font:minor-bidi;} .MsoPapDefault 	{mso-style-type:export-only; 	margin-bottom:10.0pt; 	line-height:115%;} @page Section1 	{size:8.5in 11.0in; 	margin:1.0in 1.0in 1.0in 1.0in; 	mso-header-margin:.5in; 	mso-footer-margin:.5in; 	mso-paper-source:0;} div.Section1 	{page:Section1;}  /* List Definitions */  @list l0 	{mso-list-id:166099303; 	mso-list-type:hybrid; 	mso-list-template-ids:-2040099492 67698699 67698691 67698693 67698689 67698691 67698693 67698689 67698691 67698693;} @list l0:level1 	{mso-level-number-format:bullet; 	mso-level-text:; 	mso-level-tab-stop:none; 	mso-level-number-position:left; 	margin-left:1.0in; 	text-indent:-.25in; 	font-family:Wingdings;} ol 	{margin-bottom:0in;} ul 	{margin-bottom:0in;} --><!--[if gte mso 10]&gt; &lt;!   /* Style Definitions */  table.MsoNormalTable 	{mso-style-name:"Table Normal"; 	mso-tstyle-rowband-size:0; 	mso-tstyle-colband-size:0; 	mso-style-noshow:yes; 	mso-style-priority:99; 	mso-style-qformat:yes; 	mso-style-parent:""; 	mso-padding-alt:0in 5.4pt 0in 5.4pt; 	mso-para-margin-top:0in; 	mso-para-margin-right:0in; 	mso-para-margin-bottom:10.0pt; 	mso-para-margin-left:0in; 	line-height:115%; 	mso-pagination:widow-orphan; 	font-size:11.0pt; 	font-family:"Calibri","sans-serif"; 	mso-ascii-font-family:Calibri; 	mso-ascii-theme-font:minor-latin; 	mso-hansi-font-family:Calibri; 	mso-hansi-theme-font:minor-latin;} --> <!--[endif]-->
<p class="MsoListParagraph" style="margin-left:1in;text-indent:-.25in;"><!--[if !supportLists]-->They are so enthusiastic about giving assignments and making us scratch our brains.</p>
</li>
<li><!--[if gte mso 9]&gt;  Normal 0     false false false  EN-US X-NONE X-NONE                           &lt;![endif]--><!--[if gte mso 9]&gt;                                                                                                                                            &lt;![endif]--><!--  /* Font Definitions */  @font-face 	{font-family:Wingdings; 	panose-1:5 0 0 0 0 0 0 0 0 0; 	mso-font-charset:2; 	mso-generic-font-family:auto; 	mso-font-pitch:variable; 	mso-font-signature:0 268435456 0 0 -2147483648 0;} @font-face 	{font-family:"Cambria Math"; 	panose-1:2 4 5 3 5 4 6 3 2 4; 	mso-font-charset:0; 	mso-generic-font-family:roman; 	mso-font-pitch:variable; 	mso-font-signature:-1610611985 1107304683 0 0 159 0;} @font-face 	{font-family:Calibri; 	panose-1:2 15 5 2 2 2 4 3 2 4; 	mso-font-charset:0; 	mso-generic-font-family:swiss; 	mso-font-pitch:variable; 	mso-font-signature:-1610611985 1073750139 0 0 159 0;}  /* Style Definitions */  p.MsoNormal, li.MsoNormal, div.MsoNormal 	{mso-style-unhide:no; 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	mso-hansi-font-family:Calibri; 	mso-hansi-theme-font:minor-latin; 	mso-bidi-font-family:"Times New Roman"; 	mso-bidi-theme-font:minor-bidi;} .MsoChpDefault 	{mso-style-type:export-only; 	mso-default-props:yes; 	mso-ascii-font-family:Calibri; 	mso-ascii-theme-font:minor-latin; 	mso-fareast-font-family:Calibri; 	mso-fareast-theme-font:minor-latin; 	mso-hansi-font-family:Calibri; 	mso-hansi-theme-font:minor-latin; 	mso-bidi-font-family:"Times New Roman"; 	mso-bidi-theme-font:minor-bidi;} .MsoPapDefault 	{mso-style-type:export-only; 	margin-bottom:10.0pt; 	line-height:115%;} @page Section1 	{size:8.5in 11.0in; 	margin:1.0in 1.0in 1.0in 1.0in; 	mso-header-margin:.5in; 	mso-footer-margin:.5in; 	mso-paper-source:0;} div.Section1 	{page:Section1;}  /* List Definitions */  @list l0 	{mso-list-id:166099303; 	mso-list-type:hybrid; 	mso-list-template-ids:-2040099492 67698699 67698691 67698693 67698689 67698691 67698693 67698689 67698691 67698693;} @list l0:level1 	{mso-level-number-format:bullet; 	mso-level-text:; 	mso-level-tab-stop:none; 	mso-level-number-position:left; 	margin-left:1.0in; 	text-indent:-.25in; 	font-family:Wingdings;} ol 	{margin-bottom:0in;} ul 	{margin-bottom:0in;} --><!--[if gte mso 10]&gt; &lt;!   /* Style Definitions */  table.MsoNormalTable 	{mso-style-name:"Table Normal"; 	mso-tstyle-rowband-size:0; 	mso-tstyle-colband-size:0; 	mso-style-noshow:yes; 	mso-style-priority:99; 	mso-style-qformat:yes; 	mso-style-parent:""; 	mso-padding-alt:0in 5.4pt 0in 5.4pt; 	mso-para-margin-top:0in; 	mso-para-margin-right:0in; 	mso-para-margin-bottom:10.0pt; 	mso-para-margin-left:0in; 	line-height:115%; 	mso-pagination:widow-orphan; 	font-size:11.0pt; 	font-family:"Calibri","sans-serif"; 	mso-ascii-font-family:Calibri; 	mso-ascii-theme-font:minor-latin; 	mso-hansi-font-family:Calibri; 	mso-hansi-theme-font:minor-latin;} --> <!--[endif]-->
<p class="MsoListParagraph" style="margin-left:1in;text-indent:-.25in;"><!--[if !supportLists]-->They actually read our answer sheets (they did. Believe me)</p>
</li>
</ul>
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<p class="MsoNormal" style="text-indent:.5in;">Of the many algorithms that we studied the ones which I found really interesting were pair-wise sequence alignment algorithms. One of the basic units in biology is DNA which is a sequence of 4 letters A, C, T, G. DNA defines us. It contains the code which makes us what we are. Now comparing DNA sequences from two different organisms is really helpful in deciding the relationship between organisms. It helps biologists conclude about any common ancestry amongst them to name just one.</p>
<p class="MsoNormal" style="text-indent:.5in;">Pair-wise sequence alignment can basically be of two types. The ones aiming at global alignment and ones aiming at local alignment. Calculating a global alignment is a form of global optimization that forces the alignment to span the entire length of all query sequences. An example of this is Needleman–Wunsch algorithm. By contrast to global alignments, local alignments identify regions of similarity within long sequences that are often widely divergent overall. Let’s consider Smith- Waterman algorithm which aims to align two sequences with emphasis on local alignment. Here are the basic steps in the algorithm along with an example.</p>
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<p class="MsoNormal" style="text-indent:.5in;">Consider two DNA sequences: <span> </span>1: <strong>ACTGAAGG</strong></p>
<p class="MsoNormal" style="text-indent:.5in;"><span> </span>2: <strong>AATGGACTT </strong><span> </span></p>
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	mso-tstyle-rowband-size:0; 	mso-tstyle-colband-size:0; 	mso-style-noshow:yes; 	mso-style-priority:99; 	mso-style-qformat:yes; 	mso-style-parent:""; 	mso-padding-alt:0in 5.4pt 0in 5.4pt; 	mso-para-margin-top:0in; 	mso-para-margin-right:0in; 	mso-para-margin-bottom:10.0pt; 	mso-para-margin-left:0in; 	line-height:115%; 	mso-pagination:widow-orphan; 	font-size:11.0pt; 	font-family:"Calibri","sans-serif"; 	mso-ascii-font-family:Calibri; 	mso-ascii-theme-font:minor-latin; 	mso-hansi-font-family:Calibri; 	mso-hansi-theme-font:minor-latin;} --> <!--[endif]--></p>
<p class="MsoListParagraphCxSpFirst" style="margin-left:.75in;text-indent:-.25in;"><!--[if !supportLists]--><strong><span><span>1)<span style="font-family:&quot;font-style:normal;font-variant:normal;font-weight:normal;font-size:7pt;line-height:normal;"> </span></span></span></strong><!--[endif]--><strong>Decide upon match, mismatch scores (similarity measure, s (a, b)) and gap penalty.</strong></p>
<p class="MsoListParagraphCxSpMiddle" style="margin:0 -31.5pt 10pt 1in;"><span> </span>Let us assume the <strong>match score</strong> to be <strong>1</strong>. What we mean by this is,</p>
<p class="MsoListParagraphCxSpMiddle" style="margin:0 -31.5pt 10pt 1in;"><span> </span><span> </span>s (A, A) = s (C, C) = s (G, G) = s (T, T) = 1, where s is similarity measure.</p>
<p class="MsoListParagraphCxSpMiddle" style="margin-left:1in;">Let <strong>mismatch</strong> <strong>score</strong> to be <strong>– (1/3). </strong>What we mean by this is s (A, C) = &#8211; (1/3).</p>
<p class="MsoListParagraphCxSpLast" style="margin-left:1in;">And gap penalty = <strong>1 + k/3</strong>, where <strong>k = extent of gap</strong>. So for gap length =1, penalty = 1.3, for gap length = 2, penalty = 1.7 and so on.</p>
<p class="MsoNormal" style="text-indent:.5in;"><span style="font-size:11pt;font-family:&quot;">Here I have decided these scores randomly. But these scores are usually decided keeping <strong>biological aspects into consideration</strong>. <span> </span>What we are technically doing by deciding these scores is deciding what our <strong>distance matrix</strong> is. In this example my distance matrix is:</span></p>
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<td style="border:1pt solid black;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpFirst" style="line-height:normal;margin:0 0 .0001pt;">
</td>
<td style="border-color:black black black 0;border-style:solid solid solid none;border-width:1pt 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">A</p>
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<td style="border-color:black black black 0;border-style:solid solid solid none;border-width:1pt 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">T</p>
</td>
<td style="border-color:black black black 0;border-style:solid solid solid none;border-width:1pt 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">C</p>
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<td style="border-color:black black black 0;border-style:solid solid solid none;border-width:1pt 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpLast" style="line-height:normal;margin:0 0 .0001pt;">G</p>
</td>
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<tr>
<td style="border-color:0 black black;border-style:none solid solid;border-width:medium 1pt 1pt;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpFirst" style="line-height:normal;margin:0 0 .0001pt;">A</p>
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<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">1</p>
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<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">-0.3</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;text-align:center;margin:0 0 .0001pt;">-0.3</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpLast" style="line-height:normal;margin:0 0 .0001pt;">-0.3</p>
</td>
</tr>
<tr>
<td style="border-color:0 black black;border-style:none solid solid;border-width:medium 1pt 1pt;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpFirst" style="line-height:normal;margin:0 0 .0001pt;">T</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">-0.3</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">1</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">-0.3</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpLast" style="line-height:normal;margin:0 0 .0001pt;">-0.3</p>
</td>
</tr>
<tr>
<td style="border-color:0 black black;border-style:none solid solid;border-width:medium 1pt 1pt;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpFirst" style="line-height:normal;margin:0 0 .0001pt;">C</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">-0.3</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">-0.3</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">1</p>
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<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpLast" style="line-height:normal;margin:0 0 .0001pt;">-0.3</p>
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<tr>
<td style="border-color:0 black black;border-style:none solid solid;border-width:medium 1pt 1pt;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpFirst" style="line-height:normal;margin:0 0 .0001pt;">G</p>
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<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">-0.3</p>
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<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">-0.3</p>
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<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">-0.3</p>
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<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpLast" style="line-height:normal;margin:0 0 .0001pt;">1</p>
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	mso-tstyle-rowband-size:0; 	mso-tstyle-colband-size:0; 	mso-style-noshow:yes; 	mso-style-priority:99; 	mso-style-qformat:yes; 	mso-style-parent:""; 	mso-padding-alt:0in 5.4pt 0in 5.4pt; 	mso-para-margin-top:0in; 	mso-para-margin-right:0in; 	mso-para-margin-bottom:10.0pt; 	mso-para-margin-left:0in; 	line-height:115%; 	mso-pagination:widow-orphan; 	font-size:11.0pt; 	font-family:"Calibri","sans-serif"; 	mso-ascii-font-family:Calibri; 	mso-ascii-theme-font:minor-latin; 	mso-hansi-font-family:Calibri; 	mso-hansi-theme-font:minor-latin;} --> <!--[endif]--><strong><span><span>2)<span style="font-family:&quot;font-style:normal;font-variant:normal;font-weight:normal;font-size:7pt;line-height:normal;"> </span></span></span></strong><!--[endif]--><strong>Construct matrix.</strong></p>
<p class="MsoListParagraphCxSpFirst" style="margin-left:22.5pt;text-indent:31.5pt;"><strong> </strong><!--[if gte mso 9]&gt;  Normal 0     false false false  EN-US X-NONE X-NONE                           &lt;![endif]--><!--[if gte mso 9]&gt;                                                                                                                                            &lt;![endif]--><!--  /* Font Definitions */  @font-face 	{font-family:"Cambria Math"; 	panose-1:2 4 5 3 5 4 6 3 2 4; 	mso-font-charset:0; 	mso-generic-font-family:roman; 	mso-font-pitch:variable; 	mso-font-signature:-1610611985 1107304683 0 0 159 0;} @font-face 	{font-family:Calibri; 	panose-1:2 15 5 2 2 2 4 3 2 4; 	mso-font-charset:0; 	mso-generic-font-family:swiss; 	mso-font-pitch:variable; 	mso-font-signature:-1610611985 1073750139 0 0 159 0;}  /* Style Definitions */  p.MsoNormal, li.MsoNormal, div.MsoNormal 	{mso-style-unhide:no; 	mso-style-qformat:yes; 	mso-style-parent:""; 	margin-top:0in; 	margin-right:0in; 	margin-bottom:10.0pt; 	margin-left:0in; 	line-height:115%; 	mso-pagination:widow-orphan; 	font-size:11.0pt; 	font-family:"Calibri","sans-serif"; 	mso-ascii-font-family:Calibri; 	mso-ascii-theme-font:minor-latin; 	mso-fareast-font-family:Calibri; 	mso-fareast-theme-font:minor-latin; 	mso-hansi-font-family:Calibri; 	mso-hansi-theme-font:minor-latin; 	mso-bidi-font-family:"Times New Roman"; 	mso-bidi-theme-font:minor-bidi;} p.MsoListParagraph, li.MsoListParagraph, div.MsoListParagraph 	{mso-style-priority:34; 	mso-style-unhide:no; 	mso-style-qformat:yes; 	margin-top:0in; 	margin-right:0in; 	margin-bottom:10.0pt; 	margin-left:.5in; 	mso-add-space:auto; 	line-height:115%; 	mso-pagination:widow-orphan; 	font-size:11.0pt; 	font-family:"Calibri","sans-serif"; 	mso-ascii-font-family:Calibri; 	mso-ascii-theme-font:minor-latin; 	mso-fareast-font-family:Calibri; 	mso-fareast-theme-font:minor-latin; 	mso-hansi-font-family:Calibri; 	mso-hansi-theme-font:minor-latin; 	mso-bidi-font-family:"Times New Roman"; 	mso-bidi-theme-font:minor-bidi;} p.MsoListParagraphCxSpFirst, li.MsoListParagraphCxSpFirst, div.MsoListParagraphCxSpFirst 	{mso-style-priority:34; 	mso-style-unhide:no; 	mso-style-qformat:yes; 	mso-style-type:export-only; 	margin-top:0in; 	margin-right:0in; 	margin-bottom:0in; 	margin-left:.5in; 	margin-bottom:.0001pt; 	mso-add-space:auto; 	line-height:115%; 	mso-pagination:widow-orphan; 	font-size:11.0pt; 	font-family:"Calibri","sans-serif"; 	mso-ascii-font-family:Calibri; 	mso-ascii-theme-font:minor-latin; 	mso-fareast-font-family:Calibri; 	mso-fareast-theme-font:minor-latin; 	mso-hansi-font-family:Calibri; 	mso-hansi-theme-font:minor-latin; 	mso-bidi-font-family:"Times New Roman"; 	mso-bidi-theme-font:minor-bidi;} p.MsoListParagraphCxSpMiddle, li.MsoListParagraphCxSpMiddle, div.MsoListParagraphCxSpMiddle 	{mso-style-priority:34; 	mso-style-unhide:no; 	mso-style-qformat:yes; 	mso-style-type:export-only; 	margin-top:0in; 	margin-right:0in; 	margin-bottom:0in; 	margin-left:.5in; 	margin-bottom:.0001pt; 	mso-add-space:auto; 	line-height:115%; 	mso-pagination:widow-orphan; 	font-size:11.0pt; 	font-family:"Calibri","sans-serif"; 	mso-ascii-font-family:Calibri; 	mso-ascii-theme-font:minor-latin; 	mso-fareast-font-family:Calibri; 	mso-fareast-theme-font:minor-latin; 	mso-hansi-font-family:Calibri; 	mso-hansi-theme-font:minor-latin; 	mso-bidi-font-family:"Times New Roman"; 	mso-bidi-theme-font:minor-bidi;} p.MsoListParagraphCxSpLast, li.MsoListParagraphCxSpLast, div.MsoListParagraphCxSpLast 	{mso-style-priority:34; 	mso-style-unhide:no; 	mso-style-qformat:yes; 	mso-style-type:export-only; 	margin-top:0in; 	margin-right:0in; 	margin-bottom:10.0pt; 	margin-left:.5in; 	mso-add-space:auto; 	line-height:115%; 	mso-pagination:widow-orphan; 	font-size:11.0pt; 	font-family:"Calibri","sans-serif"; 	mso-ascii-font-family:Calibri; 	mso-ascii-theme-font:minor-latin; 	mso-fareast-font-family:Calibri; 	mso-fareast-theme-font:minor-latin; 	mso-hansi-font-family:Calibri; 	mso-hansi-theme-font:minor-latin; 	mso-bidi-font-family:"Times New Roman"; 	mso-bidi-theme-font:minor-bidi;} .MsoChpDefault 	{mso-style-type:export-only; 	mso-default-props:yes; 	mso-ascii-font-family:Calibri; 	mso-ascii-theme-font:minor-latin; 	mso-fareast-font-family:Calibri; 	mso-fareast-theme-font:minor-latin; 	mso-hansi-font-family:Calibri; 	mso-hansi-theme-font:minor-latin; 	mso-bidi-font-family:"Times New Roman"; 	mso-bidi-theme-font:minor-bidi;} .MsoPapDefault 	{mso-style-type:export-only; 	margin-bottom:10.0pt; 	line-height:115%;} @page Section1 	{size:8.5in 11.0in; 	margin:1.0in 1.0in 1.0in 1.0in; 	mso-header-margin:.5in; 	mso-footer-margin:.5in; 	mso-paper-source:0;} div.Section1 	{page:Section1;} --><!--[if gte mso 10]&gt; &lt;!   /* Style Definitions */  table.MsoNormalTable 	{mso-style-name:"Table Normal"; 	mso-tstyle-rowband-size:0; 	mso-tstyle-colband-size:0; 	mso-style-noshow:yes; 	mso-style-priority:99; 	mso-style-qformat:yes; 	mso-style-parent:""; 	mso-padding-alt:0in 5.4pt 0in 5.4pt; 	mso-para-margin-top:0in; 	mso-para-margin-right:0in; 	mso-para-margin-bottom:10.0pt; 	mso-para-margin-left:0in; 	line-height:115%; 	mso-pagination:widow-orphan; 	font-size:11.0pt; 	font-family:"Calibri","sans-serif"; 	mso-ascii-font-family:Calibri; 	mso-ascii-theme-font:minor-latin; 	mso-hansi-font-family:Calibri; 	mso-hansi-theme-font:minor-latin;} --><!--[endif]-->Now in sequence alignment algorithms we create a matrix using the distance matrix. We write one sequence along one axes and other sequence along other axes. The rule in SW algorithm to fill up the matrix is as follows:</p>
<p><!--[if gte mso 9]&gt;     &lt;![endif]--></p>
<p><!--[if gte mso 9]&gt;  Normal 0     false false false  EN-US X-NONE X-NONE                           &lt;![endif]--><!--[if gte mso 9]&gt;                                                                                                                                            &lt;![endif]--></p>
<p class="MsoListParagraphCxSpFirst" style="margin-left:22.5pt;text-indent:31.5pt;"><span>Set <strong>H<sub>i, 0</sub> </strong></span><strong>= <span>H<sub>0, j</sub> </span>= <span>0</span></strong><span> <span>for </span><strong>1 ≤ <span>i </span>≤ <span>n</span></strong><span> and </span><strong>1 ≤ j<span> </span>≤ <span>m</span></strong><span>, where <strong>n</strong> and <strong>m</strong> are <strong>lengths</strong> of the two sequences under consideration. Then,</span></span></p>
<p class="MsoListParagraphCxSpLast" style="margin-left:22.5pt;text-indent:31.5pt;"><strong><span>H<sub>i, j </sub><span> </span>= max { { H<sub>i-1, j-1</sub> + s( a<sub>i</sub> , b<sub>j</sub> )} , max<sub>1 ≤ k ≤ i </sub>{H<sub>i-k, j </sub>- W<sub>k</sub>}, max<sub>1 ≤ k ≤ j</sub> {H<sub>i, j-k</sub> &#8211; W<sub>k</sub>}, 0}</span></strong><span>. Here <strong>W </strong>is the <strong>gap penalty</strong> and the <strong>k</strong> is the <strong>extent of gap</strong>. Initially the matrix looks like (i.e. putting 0 in row 0 and column 0): </span></p>
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  /* Style Definitions */  table.MsoNormalTable 	{mso-style-name:"Table Normal"; 	mso-tstyle-rowband-size:0; 	mso-tstyle-colband-size:0; 	mso-style-noshow:yes; 	mso-style-priority:99; 	mso-style-qformat:yes; 	mso-style-parent:""; 	mso-padding-alt:0in 5.4pt 0in 5.4pt; 	mso-para-margin-top:0in; 	mso-para-margin-right:0in; 	mso-para-margin-bottom:10.0pt; 	mso-para-margin-left:0in; 	line-height:115%; 	mso-pagination:widow-orphan; 	font-size:11.0pt; 	font-family:"Calibri","sans-serif"; 	mso-ascii-font-family:Calibri; 	mso-ascii-theme-font:minor-latin; 	mso-hansi-font-family:Calibri; 	mso-hansi-theme-font:minor-latin;} table.MsoTableGrid 	{mso-style-name:"Table Grid"; 	mso-tstyle-rowband-size:0; 	mso-tstyle-colband-size:0; 	mso-style-priority:59; 	mso-style-unhide:no; 	border:solid black 1.0pt; 	mso-border-themecolor:text1; 	mso-border-alt:solid black .5pt; 	mso-border-themecolor:text1; 	mso-padding-alt:0in 5.4pt 0in 5.4pt; 	mso-border-insideh:.5pt solid black; 	mso-border-insideh-themecolor:text1; 	mso-border-insidev:.5pt solid black; 	mso-border-insidev-themecolor:text1; 	mso-para-margin:0in; 	mso-para-margin-bottom:.0001pt; 	mso-pagination:widow-orphan; 	font-size:11.0pt; 	font-family:"Calibri","sans-serif"; 	mso-ascii-font-family:Calibri; 	mso-ascii-theme-font:minor-latin; 	mso-hansi-font-family:Calibri; 	mso-hansi-theme-font:minor-latin;} --> <!--[endif]--></p>
<div>
<table class="MsoTableGrid" style="border:medium none;border-collapse:collapse;height:171px;" border="1" cellspacing="0" cellpadding="0" width="298">
<tbody>
<tr>
<td style="border:1pt solid black;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpFirst" style="line-height:normal;text-align:right;margin:0 0 .0001pt;">
</td>
<td style="border-color:black black black 0;border-style:solid solid solid none;border-width:1pt 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">-</p>
</td>
<td style="border-color:black black black 0;border-style:solid solid solid none;border-width:1pt 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">A</p>
</td>
<td style="border-color:black black black 0;border-style:solid solid solid none;border-width:1pt 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">C</p>
</td>
<td style="border-color:black black black 0;border-style:solid solid solid none;border-width:1pt 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">T</p>
</td>
<td style="border-color:black black black 0;border-style:solid solid solid none;border-width:1pt 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">G</p>
</td>
<td style="border-color:black black black 0;border-style:solid solid solid none;border-width:1pt 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">A</p>
</td>
<td style="border-color:black black black 0;border-style:solid solid solid none;border-width:1pt 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">A</p>
</td>
<td style="border-color:black black black 0;border-style:solid solid solid none;border-width:1pt 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">G</p>
</td>
<td style="border-color:black black black 0;border-style:solid solid solid none;border-width:1pt 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpLast" style="line-height:normal;margin:0 0 .0001pt;">G</p>
</td>
</tr>
<tr>
<td style="border-color:0 black black;border-style:none solid solid;border-width:medium 1pt 1pt;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpFirst" style="line-height:normal;margin:0 0 .0001pt;">-</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">0</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">0</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">0</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">0</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">0</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">0</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">0</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">0</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpLast" style="line-height:normal;margin:0 0 .0001pt;">0</p>
</td>
</tr>
<tr>
<td style="border-color:0 black black;border-style:none solid solid;border-width:medium 1pt 1pt;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpFirst" style="line-height:normal;margin:0 0 .0001pt;">A</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">0</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">?</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpLast" style="line-height:normal;margin:0 0 .0001pt;">
</td>
</tr>
<tr>
<td style="border-color:0 black black;border-style:none solid solid;border-width:medium 1pt 1pt;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpFirst" style="line-height:normal;margin:0 0 .0001pt;">A</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">0</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;text-align:center;margin:0 0 .0001pt;">
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpLast" style="line-height:normal;margin:0 0 .0001pt;">
</td>
</tr>
<tr>
<td style="border-color:0 black black;border-style:none solid solid;border-width:medium 1pt 1pt;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpFirst" style="line-height:normal;margin:0 0 .0001pt;">T</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">0</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpLast" style="line-height:normal;margin:0 0 .0001pt;">
</td>
</tr>
<tr>
<td style="border-color:0 black black;border-style:none solid solid;border-width:medium 1pt 1pt;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpFirst" style="line-height:normal;margin:0 0 .0001pt;">G</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">0</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpLast" style="line-height:normal;margin:0 0 .0001pt;">
</td>
</tr>
<tr>
<td style="border-color:0 black black;border-style:none solid solid;border-width:medium 1pt 1pt;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpFirst" style="line-height:normal;margin:0 0 .0001pt;">G</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">0</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpLast" style="line-height:normal;margin:0 0 .0001pt;">
</td>
</tr>
<tr>
<td style="border-color:0 black black;border-style:none solid solid;border-width:medium 1pt 1pt;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpFirst" style="line-height:normal;margin:0 0 .0001pt;">A</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">0</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpLast" style="line-height:normal;margin:0 0 .0001pt;">
</td>
</tr>
<tr>
<td style="border-color:0 black black;border-style:none solid solid;border-width:medium 1pt 1pt;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpFirst" style="line-height:normal;margin:0 0 .0001pt;">C</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">0</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpLast" style="line-height:normal;margin:0 0 .0001pt;">
</td>
</tr>
<tr>
<td style="border-color:0 black black;border-style:none solid solid;border-width:medium 1pt 1pt;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpFirst" style="line-height:normal;margin:0 0 .0001pt;">T</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">0</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpLast" style="line-height:normal;margin:0 0 .0001pt;">
</td>
</tr>
<tr>
<td style="border-color:0 black black;border-style:none solid solid;border-width:medium 1pt 1pt;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpFirst" style="line-height:normal;margin:0 0 .0001pt;">T</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">0</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpLast" style="line-height:normal;margin:0 0 .0001pt;">
</td>
</tr>
</tbody>
</table>
</div>
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<p class="MsoListParagraphCxSpFirst" style="margin-left:22.5pt;text-indent:31.5pt;">Now let’s fill up the matrix one element at the time from top left hand corner to bottom right hand corner (always moving from left to right) using the equation given above. <span> </span>Consider the cell containing ‘?’. The corresponding letter from sequence 1 is ‘A’ and that from sequence 2 is ‘A’. Hence substituting values in our equation we have,</p>
<p class="MsoListParagraphCxSpLast" style="margin-left:22.5pt;text-indent:31.5pt;">H = max {{0 + s (A, A)}, {0-1.3}, {0-1.3}, 0} = max {1, -1.3, -1.3, 0} = 1.</p>
<p class="MsoNormal" style="margin-left:.25in;text-indent:.5in;">Similarly we can fill up other positions in matrix. Here’s one more example: Consider <strong>row 4 and column 6</strong>. The letter in sequence1 is ‘A’ and that in sequence2 is <span> </span>‘G’. So we have,</p>
<p class="MsoListParagraphCxSpFirst" style="margin-left:.75in;">H<sub>4, 6</sub> = max { {H<sub>3, 5 + </sub>s(A, G)},<span> </span>max { (H<sub>4, 5</sub> – 1.3) , (H<sub>4,4</sub> – 1.7), (H<sub>4,3 ­</sub> &#8211; 2)},<span> </span>max {(H<sub>3, 6 </sub>– 1.3), (H<sub>2,6</sub> – 1.7), (H<sub>1,6</sub>) &#8211; 2}, 0 }</p>
<p class="MsoListParagraphCxSpMiddle" style="margin-left:.75in;"><span> </span>= max {-0.3, max {0.1, 1,-1.6}, max {-0.6, 0.3, -1}, 0} = max {-0.3, 1, 0.3} = 1</p>
<p class="MsoListParagraphCxSpLast" style="margin-left:22.5pt;text-indent:31.5pt;"><span style="font-size:11pt;font-family:&quot;">Thus our final matrix is:</span></p>
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<div>
<table class="MsoTableGrid" style="border:medium none;border-collapse:collapse;height:184px;" border="1" cellspacing="0" cellpadding="0" width="315">
<tbody>
<tr>
<td style="border:1pt solid black;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpFirst" style="line-height:normal;margin:0 0 .0001pt;">
</td>
<td style="border-color:black black black 0;border-style:solid solid solid none;border-width:1pt 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">-</p>
</td>
<td style="border-color:black black black 0;border-style:solid solid solid none;border-width:1pt 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">A</p>
</td>
<td style="border-color:black black black 0;border-style:solid solid solid none;border-width:1pt 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">C</p>
</td>
<td style="border-color:black black black 0;border-style:solid solid solid none;border-width:1pt 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">T</p>
</td>
<td style="border-color:black black black 0;border-style:solid solid solid none;border-width:1pt 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">G</p>
</td>
<td style="border-color:black black black 0;border-style:solid solid solid none;border-width:1pt 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">A</p>
</td>
<td style="border-color:black black black 0;border-style:solid solid solid none;border-width:1pt 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">A</p>
</td>
<td style="border-color:black black black 0;border-style:solid solid solid none;border-width:1pt 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">G</p>
</td>
<td style="border-color:black black black 0;border-style:solid solid solid none;border-width:1pt 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpLast" style="line-height:normal;margin:0 0 .0001pt;">G</p>
</td>
</tr>
<tr>
<td style="border-color:0 black black;border-style:none solid solid;border-width:medium 1pt 1pt;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpFirst" style="line-height:normal;margin:0 0 .0001pt;">-</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">0</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">0</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">0</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">0</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">0</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">0</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">0</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">0</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpLast" style="line-height:normal;margin:0 0 .0001pt;">0</p>
</td>
</tr>
<tr>
<td style="border-color:0 black black;border-style:none solid solid;border-width:medium 1pt 1pt;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpFirst" style="line-height:normal;margin:0 0 .0001pt;">A</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">0</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">1</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">0</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">0</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;text-align:center;margin:0 0 .0001pt;">0</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">1</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">1</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">0</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpLast" style="line-height:normal;margin:0 0 .0001pt;">0</p>
</td>
</tr>
<tr>
<td style="border-color:0 black black;border-style:none solid solid;border-width:medium 1pt 1pt;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpFirst" style="line-height:normal;margin:0 0 .0001pt;">A</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">0</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">1</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">0.7</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">0</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">0</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">1</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">2</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">0.7</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpLast" style="line-height:normal;margin:0 0 .0001pt;">0.3</p>
</td>
</tr>
<tr>
<td style="border-color:0 black black;border-style:none solid solid;border-width:medium 1pt 1pt;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpFirst" style="line-height:normal;margin:0 0 .0001pt;">T</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">0</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">0</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">0.7</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">1.7</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">0.4</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">0</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">0.7</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">1.7</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpLast" style="line-height:normal;margin:0 0 .0001pt;">0.4</p>
</td>
</tr>
<tr>
<td style="border-color:0 black black;border-style:none solid solid;border-width:medium 1pt 1pt;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpFirst" style="line-height:normal;margin:0 0 .0001pt;">G</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">0</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">0</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">0</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">0.4</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">2.7</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">1.4</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">1</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">1.7</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpLast" style="line-height:normal;margin:0 0 .0001pt;">2.7</p>
</td>
</tr>
<tr>
<td style="border-color:0 black black;border-style:none solid solid;border-width:medium 1pt 1pt;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpFirst" style="line-height:normal;margin:0 0 .0001pt;">G</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">0</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">0</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">0</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">0</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">1.4</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">2.4</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">1.1</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">2</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpLast" style="line-height:normal;margin:0 0 .0001pt;">2.7</p>
</td>
</tr>
<tr>
<td style="border-color:0 black black;border-style:none solid solid;border-width:medium 1pt 1pt;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpFirst" style="line-height:normal;margin:0 0 .0001pt;">A</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">0</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">1</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">0</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">0</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">1</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">2.4</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">3.4</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">2.1</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpLast" style="line-height:normal;margin:0 0 .0001pt;">1.7</p>
</td>
</tr>
<tr>
<td style="border-color:0 black black;border-style:none solid solid;border-width:medium 1pt 1pt;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpFirst" style="line-height:normal;margin:0 0 .0001pt;">C</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">0</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">0</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">2</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">0.7</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">0.3</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">1.1</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">2.1</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">3.1</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpLast" style="line-height:normal;margin:0 0 .0001pt;">1.8</p>
</td>
</tr>
<tr>
<td style="border-color:0 black black;border-style:none solid solid;border-width:medium 1pt 1pt;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpFirst" style="line-height:normal;margin:0 0 .0001pt;">T</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">0</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">0</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">0.7</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">3</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">1.7</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">0.4</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">1.7</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">1.8</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpLast" style="line-height:normal;margin:0 0 .0001pt;">2.8</p>
</td>
</tr>
<tr>
<td style="border-color:0 black black;border-style:none solid solid;border-width:medium 1pt 1pt;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpFirst" style="line-height:normal;margin:0 0 .0001pt;">T</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">0</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">0</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">0.3</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">1.7</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">2.7</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">1.4</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">0.4</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">1.4</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpLast" style="line-height:normal;margin:0 0 .0001pt;">1.5</p>
</td>
</tr>
</tbody>
</table>
</div>
<p class="MsoNormal" style="text-indent:.5in;"><strong>3) Trace- back</strong></p>
<p class="MsoNormal" style="text-indent:.5in;"><strong> </strong><!--[if gte mso 9]&gt;  Normal 0     false false false  EN-US X-NONE X-NONE                           &lt;![endif]--><!--[if gte mso 9]&gt;                                                                                                                                            &lt;![endif]--><!--  /* Font Definitions */  @font-face 	{font-family:"Cambria Math"; 	panose-1:2 4 5 3 5 4 6 3 2 4; 	mso-font-charset:0; 	mso-generic-font-family:roman; 	mso-font-pitch:variable; 	mso-font-signature:-1610611985 1107304683 0 0 159 0;} @font-face 	{font-family:Calibri; 	panose-1:2 15 5 2 2 2 4 3 2 4; 	mso-font-charset:0; 	mso-generic-font-family:swiss; 	mso-font-pitch:variable; 	mso-font-signature:-1610611985 1073750139 0 0 159 0;}  /* Style Definitions */  p.MsoNormal, li.MsoNormal, div.MsoNormal 	{mso-style-unhide:no; 	mso-style-qformat:yes; 	mso-style-parent:""; 	margin-top:0in; 	margin-right:0in; 	margin-bottom:10.0pt; 	margin-left:0in; 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<p class="MsoListParagraphCxSpFirst" style="margin-left:.75in;">The next step is to trace a path in this matrix which will give us the optimal local alignment. The steps here are:</p>
<p class="MsoListParagraphCxSpMiddle" style="margin-left:1.25in;text-indent:-.25in;"><!--[if !supportLists]--><span><span>a)<span style="font-family:&quot;font-style:normal;font-variant:normal;font-weight:normal;font-size:7pt;line-height:normal;"> </span></span></span><!--[endif]-->Locate the <strong>maximum element</strong> and <strong>start</strong> the trace from that cell.</p>
<p class="MsoListParagraphCxSpMiddle" style="margin-left:1.25in;text-indent:-.25in;"><!--[if !supportLists]--><span><span>b)<span style="font-family:&quot;font-style:normal;font-variant:normal;font-weight:normal;font-size:7pt;line-height:normal;"> </span></span></span><!--[endif]-->Now check the diagonal (i-1, j-1), immediate left (i , j-1) and immediate top(i-1, j). Move to the maximum of these 3 and <strong>choose diagonal element in case of a tie</strong>.</p>
<p class="MsoListParagraphCxSpLast" style="margin-left:1.25in;text-indent:-.25in;"><!--[if !supportLists]--><span><span>c)<span style="font-family:&quot;font-style:normal;font-variant:normal;font-weight:normal;font-size:7pt;line-height:normal;"> </span></span></span><!--[endif]--><strong>Stop the trace</strong> when you reach a stage where a <strong>diagonal element is 0</strong>.</p>
<p class="MsoNormal" style="margin-left:1in;">The trace path in the matrix is shown with bold numbers.</p>
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<div>
<table class="MsoTableGrid" style="border:medium none;border-collapse:collapse;text-align:center;height:166px;" border="1" cellspacing="0" cellpadding="0" width="344">
<tbody>
<tr>
<td style="border:1pt solid black;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpFirst" style="line-height:normal;text-align:center;margin:0 0 .0001pt;">
</td>
<td style="border-color:black black black 0;border-style:solid solid solid none;border-width:1pt 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">-</p>
</td>
<td style="border-color:black black black 0;border-style:solid solid solid none;border-width:1pt 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">A</p>
</td>
<td style="border-color:black black black 0;border-style:solid solid solid none;border-width:1pt 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">C</p>
</td>
<td style="border-color:black black black 0;border-style:solid solid solid none;border-width:1pt 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">T</p>
</td>
<td style="border-color:black black black 0;border-style:solid solid solid none;border-width:1pt 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">G</p>
</td>
<td style="border-color:black black black 0;border-style:solid solid solid none;border-width:1pt 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">A</p>
</td>
<td style="border-color:black black black 0;border-style:solid solid solid none;border-width:1pt 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">A</p>
</td>
<td style="border-color:black black black 0;border-style:solid solid solid none;border-width:1pt 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">G</p>
</td>
<td style="border-color:black black black 0;border-style:solid solid solid none;border-width:1pt 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpLast" style="line-height:normal;margin:0 0 .0001pt;">G</p>
</td>
</tr>
<tr>
<td style="border-color:0 black black;border-style:none solid solid;border-width:medium 1pt 1pt;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpFirst" style="line-height:normal;margin:0 0 .0001pt;">-</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">0</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">0</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">0</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">0</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">0</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">0</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">0</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">0</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpLast" style="line-height:normal;margin:0 0 .0001pt;">0</p>
</td>
</tr>
<tr>
<td style="border-color:0 black black;border-style:none solid solid;border-width:medium 1pt 1pt;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpFirst" style="line-height:normal;margin:0 0 .0001pt;">A</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">0</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;"><strong>1</strong></p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">0</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">0</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">0</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">1</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">1</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">0</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpLast" style="line-height:normal;margin:0 0 .0001pt;">0</p>
</td>
</tr>
<tr>
<td style="border-color:0 black black;border-style:none solid solid;border-width:medium 1pt 1pt;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpFirst" style="line-height:normal;margin:0 0 .0001pt;">A</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">0</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">1</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;"><strong>0.7</strong></p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">0</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">0</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">1</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">2</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">0.7</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpLast" style="line-height:normal;margin:0 0 .0001pt;">0.3</p>
</td>
</tr>
<tr>
<td style="border-color:0 black black;border-style:none solid solid;border-width:medium 1pt 1pt;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpFirst" style="line-height:normal;margin:0 0 .0001pt;">T</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">0</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">0</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">0.7</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;"><strong>1.7</strong></p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">0.4</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">0</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">0.7</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">1.7</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpLast" style="line-height:normal;margin:0 0 .0001pt;">0.4</p>
</td>
</tr>
<tr>
<td style="border-color:0 black black;border-style:none solid solid;border-width:medium 1pt 1pt;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpFirst" style="line-height:normal;margin:0 0 .0001pt;">G</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">0</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">0</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">0</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">0.4</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;"><strong>2.7</strong></p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">1.4</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">1</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">1.7</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpLast" style="line-height:normal;margin:0 0 .0001pt;">2.7</p>
</td>
</tr>
<tr>
<td style="border-color:0 black black;border-style:none solid solid;border-width:medium 1pt 1pt;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpFirst" style="line-height:normal;margin:0 0 .0001pt;">G</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">0</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">0</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">0</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">0</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">1.4</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;"><strong>2.4</strong></p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">1.1</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">2</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpLast" style="line-height:normal;margin:0 0 .0001pt;">2.7</p>
</td>
</tr>
<tr>
<td style="border-color:0 black black;border-style:none solid solid;border-width:medium 1pt 1pt;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpFirst" style="line-height:normal;margin:0 0 .0001pt;">A</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">0</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">1</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">0</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">0</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">1</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">2.4</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;"><strong>3.4</strong></p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">2.1</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpLast" style="line-height:normal;margin:0 0 .0001pt;">1.7</p>
</td>
</tr>
<tr>
<td style="border-color:0 black black;border-style:none solid solid;border-width:medium 1pt 1pt;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpFirst" style="line-height:normal;margin:0 0 .0001pt;">C</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">0</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">0</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">2</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">0.7</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">0.3</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">1.1</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">2.1</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">3.1</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpLast" style="line-height:normal;margin:0 0 .0001pt;">1.8</p>
</td>
</tr>
<tr>
<td style="border-color:0 black black;border-style:none solid solid;border-width:medium 1pt 1pt;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpFirst" style="line-height:normal;margin:0 0 .0001pt;">T</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">0</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">0</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">0.7</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">3</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">1.7</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">0.4</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">1.7</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">1.8</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpLast" style="line-height:normal;margin:0 0 .0001pt;">2.8</p>
</td>
</tr>
<tr>
<td style="border-color:0 black black;border-style:none solid solid;border-width:medium 1pt 1pt;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpFirst" style="line-height:normal;margin:0 0 .0001pt;">T</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">0</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">0</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">0.3</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">1.7</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">2.7</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">1.4</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">0.4</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpMiddle" style="line-height:normal;margin:0 0 .0001pt;">1.4</p>
</td>
<td style="border-color:0 black black 0;border-style:none solid solid none;border-width:medium 1pt 1pt medium;padding:0 5.4pt;" valign="top">
<p class="MsoListParagraphCxSpLast" style="line-height:normal;margin:0 0 .0001pt;">1.5</p>
</td>
</tr>
</tbody>
</table>
</div>
<p class="MsoNormal" style="text-indent:.5in;"><strong>4) Alignment</strong></p>
<p class="MsoNormal" style="text-indent:.5in;"><strong> </strong><!--[if gte mso 9]&gt;  Normal 0     false false false  EN-US X-NONE X-NONE                           &lt;![endif]--><!--[if gte mso 9]&gt;                                                                                                                                            &lt;![endif]--><!--  /* Font Definitions */  @font-face 	{font-family:Wingdings; 	panose-1:5 0 0 0 0 0 0 0 0 0; 	mso-font-charset:2; 	mso-generic-font-family:auto; 	mso-font-pitch:variable; 	mso-font-signature:0 268435456 0 0 -2147483648 0;} @font-face 	{font-family:"Cambria Math"; 	panose-1:2 4 5 3 5 4 6 3 2 4; 	mso-font-charset:0; 	mso-generic-font-family:roman; 	mso-font-pitch:variable; 	mso-font-signature:-1610611985 1107304683 0 0 159 0;} @font-face 	{font-family:Calibri; 	panose-1:2 15 5 2 2 2 4 3 2 4; 	mso-font-charset:0; 	mso-generic-font-family:swiss; 	mso-font-pitch:variable; 	mso-font-signature:-1610611985 1073750139 0 0 159 0;}  /* Style Definitions */  p.MsoNormal, li.MsoNormal, div.MsoNormal 	{mso-style-unhide:no; 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<p class="MsoListParagraphCxSpFirst" style="margin-left:1in;">This is the last step. Using the trace- back we have our maximum similar segment as:</p>
<p class="MsoListParagraphCxSpMiddle" style="margin-left:1in;"><span> </span><span> </span>&#8211;ACTGAA&#8211;</p>
<p class="MsoListParagraphCxSpMiddle" style="margin-left:1in;"><span> </span>&#8211;AATGGA&#8211;<span> </span></p>
<p class="MsoListParagraphCxSpLast" style="margin-left:1in;">Our alignment has 4 matches, 2 mismatches and no gaps.</p>
<p class="MsoNormal"><span> </span>So this was about Smith – Waterman Algorithm. Thanks to my faculty and Swati (we usually end up fighting trying to figure out how things work before happily coming to a consensus) I hope I have got things right. Also here’s the link to the original paper by Smith which is very well written (and I don’t say that about every paper I go through) : <a href="http://www-hto.usc.edu/papers/msw_papers/msw-040.pdf">http://www-hto.usc.edu/papers/msw_papers/msw-040.pdf</a>.</p>
<p class="MsoNormal"><span> </span><span> </span>I referred this paper and it has NW algorithm explained as well.</p>
<p class="MsoNormal" style="text-indent:.5in;">
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<p class="MsoListParagraph" style="margin-left:.75in;"><strong></strong></p>
<p class="MsoNormal" style="text-indent:.5in;"><span style="font-size:11pt;font-family:&quot;"><br />
</span></p>
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			<media:title type="html">shaizeen</media:title>
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		<title>Developers Conference @ COEP</title>
		<link>http://shaizeen.wordpress.com/2009/01/21/developers-conference-coep/</link>
		<comments>http://shaizeen.wordpress.com/2009/01/21/developers-conference-coep/#comments</comments>
		<pubDate>Wed, 21 Jan 2009 04:19:00 +0000</pubDate>
		<dc:creator>ShaiZeen</dc:creator>
				<category><![CDATA[Events]]></category>
		<category><![CDATA[Personal]]></category>
		<category><![CDATA[DEVCON]]></category>
		<category><![CDATA[Microsoft Student Partners]]></category>

		<guid isPermaLink="false">http://shaizeen.wordpress.com/?p=36</guid>
		<description><![CDATA[Its being almost a month since I last blogged. This being my first one since the beginning of 2009. The one thing which I dont understand about education system is why do academic year and calendar year dont start and end at the same time. Its new year and I am still in BTECH IT [...]<img alt="" border="0" src="http://stats.wordpress.com/b.gif?host=shaizeen.wordpress.com&amp;blog=5427472&amp;post=36&amp;subd=shaizeen&amp;ref=&amp;feed=1" width="1" height="1" />]]></description>
			<content:encoded><![CDATA[<p>Its being almost a month since I last blogged. This being my first one since the beginning of 2009. The one thing which I dont understand about education system is why do academic year and calendar year dont start and end at the same time. Its new year and I am still in BTECH IT at COEP as was I last year. So many things in your life just don&#8217;t seem to change though there are people out there celebrating an entire new year!! I spend my new year eve with Anju, my childhood friend and her family at her home. She is one of my best buddies and its always a treat to spend time with her.They have been a family to me ever since I moved to Pune and it is thanks to them that I never feel I am alone in this city.</p>
<p>My BE project cum internship at NVIDIA keeps me busy enough that many a times I end up being in office sometimes even at weekends inspite of spending my weekdays almost entirely there. I had vowed that I will never spent weekends in office. Trups (my roomie since the first day at hostel) who was the sole witness to my &#8220;resolution&#8221; has gone at length to suggest that I rent a room near office to avoid commuting. Not that she cares about me hitting someone while being &#8220;activated&#8221; (which I actually did a few days ago) but more that she likes to remind me that I am a workaholic in a very tactful way.  And trust me as far as  &#8220;hitting&#8221; (pun intended) goes, it can be mutual as is certainly always in my case <img src='http://s0.wp.com/wp-includes/images/smilies/icon_smile.gif' alt=':)' class='wp-smiley' />  .</p>
<p>But what better to start your new year than to be part of an amazing event which took place at my college auditorium.Each year we Microsoft Student Partners from Pune organise <strong>Dev</strong>elopers <strong>Con</strong>ference (DEVCON) , a day filled with technical sessions and fun for colleges in Pune. This year we had organised DEVCON on 18th Jan and the response was huge. More than 1000 students turned up from in and around the entire city. We organisers were indeed overwhelmed!!</p>
<p>The entire team had worked hard to make this event successful and we all were really happy with the turnout. Here are some pics:</p>
<div id="attachment_40" class="wp-caption alignleft" style="width: 138px"><img class="size-thumbnail wp-image-40" title="Students lined up at COEP auditorium" src="http://shaizeen.files.wordpress.com/2009/01/line1.jpg?w=128&#038;h=96" alt="Students lined up at COEP auditorium" width="128" height="96" /><p class="wp-caption-text">Students lined up at COEP auditoriu</p></div>
<div id="attachment_41" class="wp-caption alignright" style="width: 138px"><img class="size-thumbnail wp-image-41" title="Packed Auditorium @ COEP" src="http://shaizeen.files.wordpress.com/2009/01/audi1.jpg?w=128&#038;h=96" alt="Packed Auditorium @ COEP" width="128" height="96" /><p class="wp-caption-text">Packed Auditorium @ COEP</p></div>
<div id="attachment_42" class="wp-caption aligncenter" style="width: 138px"><img class="size-thumbnail wp-image-42" title="Quiz @ DEVCON" src="http://shaizeen.files.wordpress.com/2009/01/quiz.jpg?w=128&#038;h=96" alt="Quiz @ DEVCON" width="128" height="96" /><p class="wp-caption-text">Quiz @ DEVCON</p></div>
<p>And yes finally here are we the MSP&#8217;s, the ultimate ROCKERS!!</p>
<div id="attachment_43" class="wp-caption aligncenter" style="width: 310px"><img class="size-medium wp-image-43" title="Microsoft Student Partners, Pune" src="http://shaizeen.files.wordpress.com/2009/01/us.jpg?w=300&#038;h=225" alt="Microsoft Student Partners, Pune" width="300" height="225" /><p class="wp-caption-text">Microsoft Student Partners, Pune</p></div>
<p>( left to right)  Prachi, Manish, Ravikant, Shristi,Anuja, Dev, Awadesh, Piyusha, Abin,Dhaval , Sonali , Me,</p>
<p>( right to left) Rashi, Pradyna, Nikhil, Mayur, Aniket,Anand, Rahul, Ritesh.</p>
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			<media:title type="html">Students lined up at COEP auditorium</media:title>
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			<media:title type="html">Packed Auditorium @ COEP</media:title>
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			<media:title type="html">Quiz @ DEVCON</media:title>
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		<title>Aspire..Achieve .. Be the change&#8230;</title>
		<link>http://shaizeen.wordpress.com/2008/12/19/aspireachieve-be-the-change/</link>
		<comments>http://shaizeen.wordpress.com/2008/12/19/aspireachieve-be-the-change/#comments</comments>
		<pubDate>Fri, 19 Dec 2008 16:56:52 +0000</pubDate>
		<dc:creator>ShaiZeen</dc:creator>
				<category><![CDATA[Personal]]></category>
		<category><![CDATA[Teach India]]></category>

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		<description><![CDATA[There is no denying the important role education plays in our lives. One of the hindrances in India’s growth is illiteracy. I always wanted to contribute my bit in this regard but my studies and my work kept me from doing something for this cause. One day I came across this add in TOI about [...]<img alt="" border="0" src="http://stats.wordpress.com/b.gif?host=shaizeen.wordpress.com&amp;blog=5427472&amp;post=31&amp;subd=shaizeen&amp;ref=&amp;feed=1" width="1" height="1" />]]></description>
			<content:encoded><![CDATA[<p><!--[if gte mso 9]&gt;  Normal 0     false false false  EN-US X-NONE X-NONE                           &lt;![endif]--><!--[if gte mso 9]&gt;                                                                                                                                            &lt;![endif]--></p>
<p class="MsoNormal">There is no denying the important role education plays in our lives. One of the hindrances in India’s growth is illiteracy. I always wanted to contribute my bit in this regard but my studies and my work kept me from doing something for this cause.</p>
<p class="MsoNormal"><span> </span>One day I came across this add in TOI about “Teach India”. Herein you were required to spent just 2-3 hours per week teaching kids from less privilleged background. As soon as my exams ended I applied for it. Based on your preference of location, you are allocated an NGO with whom you get associated. I was allocated “Akanksha”. After an introductory session and an orientation session I was allocated a center where I could go and assist the teacher in teaching kids.</p>
<p class="MsoNormal"><span> </span>Wednesday was my first day as a volunteer.. I was excited but at the same time nervous!! Kids and me? I was always too disciplined. As kids, my cousins would never consider me as a probable accomplice in any of their plans. (My brother has long given up attempts to bring some disorder in me!!) Not that I don’t deal with people at all. I have been part of various teams right from school, heading them most often. But this was different. Kids belong to a different world altogether. A world where there is no limits to imagination, where innocence prevails to an extent that even absurd questions are asked in a plain way!!</p>
<p class="MsoNormal"><span> </span>I was right on time at the Akanksha Centre. Soon a marching brigade of kids in Akanksha t-shirts arrived. The teachers at the centre made sure that the kids walked in the centre in a line. As soon as we entered the center the kids occupied their predefined seating positions. The teacher announced my presence and it was amazing to see that the class rules were explained one by one by the kids themselves.</p>
<p class="MsoNormal" style="text-indent:.5in;">The teacher then told me that we would start by playing a game called “Hot seat”. She said this is how kids would know me. As per the game, kids would ask me questions and I would answer them. And trust me there stood Shaiz completely stumped!! Shaiz who never minds going in first for vivas, Shaiz who never prepared for her interviews was stumped by the questionaire of mere toddlers!! “So why do you like red?” “Are you married?”. On being asked “which is your favourite story?” I couldn’t think of any other than Rowling’s Harry Potter series to which their answer was “Most of the didis like the same one..we already know it!!”</p>
<p class="MsoNormal"><span> </span>Dealing with kids is by no means an easy task. I knew this beforehand but experienced it as well!! What amazed me the most was the enthusiam of the teacher at the center. Her liveliness and the personal attention she was giving to each of them kept them all interested in what was happening in the class. We taught the kids prepositions and some basics of computers.</p>
<p class="MsoNormal"><span> </span>All in all it was a very different experience for me. <span> </span>I really am looking forward to interacting with the kids next week!!</p>
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		<title>My First Love</title>
		<link>http://shaizeen.wordpress.com/2008/12/14/my-first-love/</link>
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		<pubDate>Sun, 14 Dec 2008 17:12:03 +0000</pubDate>
		<dc:creator>ShaiZeen</dc:creator>
				<category><![CDATA[Algorithms]]></category>
		<category><![CDATA[Technical]]></category>
		<category><![CDATA[Heap]]></category>
		<category><![CDATA[Heap sort]]></category>
		<category><![CDATA[My First Love]]></category>

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		<description><![CDATA[The time I saw him I was bound to fall in love. Such an amazing behavior!! Such a consistent performance!! Unbeatable, I told Swati. She was still scrutinizing him (No, he is not an athlete).This post is about my very first love. I am a computer science engineer (There you raise your eyebrows.) I mean [...]<img alt="" border="0" src="http://stats.wordpress.com/b.gif?host=shaizeen.wordpress.com&amp;blog=5427472&amp;post=16&amp;subd=shaizeen&amp;ref=&amp;feed=1" width="1" height="1" />]]></description>
			<content:encoded><![CDATA[<p class="MsoNormal" style="text-indent:.5in;">The time I saw him I was bound to fall in love. Such an amazing behavior!! Such a consistent performance!! Unbeatable, I told Swati. She was still scrutinizing him (No, he is not an athlete).This post is about my very first love.</p>
<p class="MsoNormal">I am a computer science engineer (There you raise your eyebrows.) I mean I am positive I will be one in about 7 months. I don’t believe in fuzzy logic (as of now.. Life has taught me ‘never say never!’). I don’t think I can have a crush. Either I am in love, or I am not. And yes. This was for sure love.</p>
<p class="MsoNormal" style="text-indent:.5in;">He is a Heap. Oh you never heard of him? Or if you did you think he is not friendly? Oh no. He is the most friendly data structure around. Arrays, link-list no one comes even close to performance that Heap offers. So wanna know more about him? Read on.</p>
<p class="MsoNormal" style="text-indent:.5in;"><span>Heap<strong><em> </em></strong>data structure is an array object that can be viewed as a nearly complete binary tree. (The tree is completely filled on all levels except possibly the lowest, which is filled from the left up to a point) If heap is an array object then what makes it different?? There is an interesting property that differentiates a heap from an array and that it is: key stored in parent node should be less than the key stored in any of its children. This is an example of a min-heap. Heaps are two kinds, <strong>min-heaps</strong> and <strong>max-heap</strong>. Max-heap being one in which the parent has key value greater than the any of its children. Here’s an example:</span></p>
<p class="MsoNormal" style="text-indent:.5in;">
<p><img class="aligncenter size-medium wp-image-17" title="Max-Heap" src="http://shaizeen.files.wordpress.com/2008/12/im1.jpg?w=300&#038;h=203" alt="Max-Heap" width="300" height="203" /></p>
<p class="MsoListParagraphCxSpFirst" style="margin-left:.75in;text-indent:-.25in;">a)Max heap viewed as a binary tree b) Max heap in its array representation</p>
<p class="MsoListParagraphCxSpLast" style="margin-left:.75in;">(Each node with two children)</p>
<p class="MsoNormal" style="text-indent:.5in;">Any data structure is judged by the asymptotic complexity involved in various operations that we perform on it, which includes create, search, insert, delete. Let’s analyze each of these in turn.</p>
<p class="MsoNormal" style="text-indent:.5in;"><strong>Create:</strong></p>
<p class="MsoNormal" style="text-indent:.5in;">Consider that we are building a max-heap (binary). Our input is an array with arbitrary elements and we ought to make sure that the ‘heap property’ is valid i.e. each parent node holds a key greater than any of its children (in this case 2 children). Now if we observe in the diagram above parent nodes / internal nodes begin from position 5. Given n nodes/elements, internal nodes begin at array position n/2. (Assuming array indexes start from 1. If we take this to be 0, this will change to (n/2-1)).</p>
<p class="MsoNormal" style="text-indent:.5in;">Now to create heap all we got to do is start scanning the array from the last internal node (index =n/2) to index 1 and check if ‘heap property is satisfied or not. Anytime we find that the heap property is violated we ought to swap the nodes. Here’s a pictorial representation of this procedure:</p>
<p class="MsoNormal" style="text-indent:.5in;">
<p class="MsoNormal" style="text-indent:.5in;"><img class="aligncenter size-medium wp-image-22" title="Creation of max-heap" src="http://shaizeen.files.wordpress.com/2008/12/im21.jpg?w=300&#038;h=259" alt="Creation of max-heap" width="300" height="259" /></p>
<p class="MsoNormal" style="text-indent:.5in;"><strong>A:</strong> initial array <strong>a)</strong> 16 compared with 7, no swap. <strong>b)</strong> 2 compared with 14 and 8, the larger node 14 is swapped with 2. This ensures heap property is not violated as 14 &gt;8. <strong>c) </strong>3 and 10 are swapped. <strong>d)</strong> 1 and 16 swapped <strong>e)</strong> 4 and 16 swapped <strong>f)</strong> the final max-heap.</p>
<p class="MsoNormal" style="text-indent:.5in;">The asymptotic complexity of building heap is O (n).</p>
<p class="MsoNormal" style="text-indent:.5in;"><strong>Insert: </strong></p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;"><span>To insert an element into the heap just place it in the next empty array location and let it bubble up the tree till heap property is not satisfied. Since height of heap (in binary tree representation) is O (log n), complexity of insert is O (log n).</span></p>
<p class="MsoNormal" style="text-indent:.5in;"><strong>Delete:</strong></p>
<p class="MsoNormal" style="text-indent:.5in;">Deleting a leaf from heap is straightforward. When it comes to deleting an internal node, replace it with the larger of its two children and continue this down the tree. Again since height of heap (represented as binary tree) is O (log n), complexity of delete is O(log n).</p>
<p class="MsoNormal" style="text-indent:.5in;"><strong>Search:</strong></p>
<p class="MsoNormal" style="text-indent:.5in;">Searching the heap is <strong>O (n)</strong> i.e. you can search a heap in linear time as you do in arrays or link-list.</p>
<p class="MsoNormal" style="text-indent:.5in;">Heaps have huge applications in numerous algorithms cause of their property to give the minimum /maximum of a set of elements in constant amount of time (O(1)).If you have observed carefully in a max-heap we always get the largest element of the array in array index 1. So we can use this property to sort numbers as follows:</p>
<p class="MsoListParagraphCxSpFirst" style="margin-left:1.25in;text-indent:-.25in;">1)Form heap from n input elements: <strong>O(n)</strong></p>
<p class="MsoListParagraphCxSpMiddle" style="margin-left:1.25in;text-indent:-.25in;">2)Delete the element at array index 1 (this is the largest element) : <strong>O(1)</strong></p>
<p class="MsoListParagraphCxSpMiddle" style="margin-left:1in;">3)Adjust the heap with n-1 elements<strong>. O (log n). </strong>(As we saw above deleting an element and readjusting heap is O(log n))</p>
<p class="MsoListParagraphCxSpLast" style="margin-left:1.25in;text-indent:-.25in;">4)Repeat from step 2 till 1 element is left in heap.</p>
<p class="MsoNormal" style="text-align:justify;text-indent:.5in;">This is my favorite sorting algorithm. It is called the Heapsort and it is an optimal sorting algorithm. The overall complexity of this algorithm is O (n log n) cause we adjust the heap n times (after deleting element at array index 1 to get the largest in present set)<strong>.</strong></p>
<p class="MsoNormal" style="text-indent:.5in;"><span>So this was all about Heap. Trust me once you know him well you really can’t stop falling in love with him!</span></p>
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		<title>Shaiz&#8230;.Activated!!!</title>
		<link>http://shaizeen.wordpress.com/2008/12/01/shaizactivated/</link>
		<comments>http://shaizeen.wordpress.com/2008/12/01/shaizactivated/#comments</comments>
		<pubDate>Mon, 01 Dec 2008 03:00:22 +0000</pubDate>
		<dc:creator>ShaiZeen</dc:creator>
				<category><![CDATA[Events]]></category>

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		<description><![CDATA[Yes&#8230;&#8230;Shaiz is Activated!! Not long ago, ie approximately for 2 months I was completely grounded.Reason : Submissions and exams.But now I am so relieved. My exams are over and though I am not completely free (my NVIDIA internship is back in full swing) atleast I am not completely tied up. One really important developement in [...]<img alt="" border="0" src="http://stats.wordpress.com/b.gif?host=shaizeen.wordpress.com&amp;blog=5427472&amp;post=11&amp;subd=shaizeen&amp;ref=&amp;feed=1" width="1" height="1" />]]></description>
			<content:encoded><![CDATA[<p>Yes&#8230;&#8230;Shaiz is Activated!! Not long ago, ie approximately for 2 months I was completely grounded.Reason : Submissions and exams.But now I am so relieved. My exams are over and though I am not completely free (my NVIDIA internship is back in full swing) atleast I am not completely tied up.</p>
<p>One really important developement in my life right now is my parent&#8217;s gift on my 20th birthday. They gifted me a Honda Activa.Jeez! She is cute and fast. And she really has put my life in the fast lane. So here I stand fully &#8220;activated&#8221; thanks to my dear parents.</p>
<p style="text-align:center;">
<div class="wp-caption aligncenter" style="width: 624px"><img title="Activa" src="http://shaizeen.files.wordpress.com/2008/12/bike1.jpg?w=614&#038;h=768" alt="My bike" width="614" height="768" /><p class="wp-caption-text">My bike</p></div>
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